Literature DB >> 18724929

Silencing HIV-1 In Vivo.

Frank Kirchhoff1.   

Abstract

RNA interference holds great promise for antiviral therapy, but delivering effective quantities of small interfering RNAs (siRNAs) into the right target cells in vivo represents a major challenge. Kumar et al. (2008) now report a technique to target siRNAs specifically to T cells to suppress viral infection in a humanized mouse model of HIV/AIDS.

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Year:  2008        PMID： 18724929     DOI： 10.1016/j.cell.2008.08.004

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  10 in total

Review 1.  Strategies for targeted nonviral delivery of siRNAs in vivo.

Authors:  Sang-Soo Kim; Himanshu Garg; Anjali Joshi; N Manjunath
Journal:  Trends Mol Med       Date:  2009-10-19       Impact factor: 11.951

Review 2.  RNA interference-based therapeutics for human immunodeficiency virus HIV-1 treatment: synthetic siRNA or vector-based shRNA?

Authors:  Sandesh Subramanya; Sang-Soo Kim; N Manjunath; Premlata Shankar
Journal:  Expert Opin Biol Ther       Date:  2010-02       Impact factor: 4.388

3.  Modulation of HIV pathogenesis and T-cell signaling by HIV-1 Nef.

Authors:  Shailendra K Saxena; Gaurav Shrivastava; Sneham Tiwari; Ml Arvinda Swamy; Madhavan Pn Nair
Journal:  Future Virol       Date:  2012-06-01       Impact factor: 1.831

4.  Dendronized gold nanoparticles for siRNA delivery.

Authors:  Sung Tae Kim; Apiwat Chompoosor; Yi-Cheun Yeh; Sarit S Agasti; David J Solfiell; Vincent M Rotello
Journal:  Small       Date:  2012-08-08       Impact factor: 13.281

5.  Human serum albumin-coated lipid nanoparticles for delivery of siRNA to breast cancer.

Authors:  Longzhu Piao; Hong Li; Lesheng Teng; Bryant C Yung; Yasuro Sugimoto; Robert W Brueggemeier; Robert J Lee
Journal:  Nanomedicine       Date:  2012-04-26       Impact factor: 5.307

6.  Topoisomerase II β Gene Specific siRNA Delivery by Nanoparticles Prepared with c-ter Apotransferrin and its Effect on HIV-1 Replication.

Authors:  Lokeswara Bala Krishna Sunnam; Anand K Kondapi
Journal:  Mol Biotechnol       Date:  2021-05-16       Impact factor: 2.695

7.  Silencing early viral replication in macrophages and dendritic cells effectively suppresses flavivirus encephalitis.

Authors:  Chunting Ye; Sojan Abraham; Haoquan Wu; Premlata Shankar; N Manjunath
Journal:  PLoS One       Date:  2011-03-15       Impact factor: 3.240

8.  Stability, Intracellular Delivery, and Release of siRNA from Chitosan Nanoparticles Using Different Cross-Linkers.

Authors:  Maria Abdul Ghafoor Raja; Haliza Katas; Thum Jing Wen
Journal:  PLoS One       Date:  2015-06-11       Impact factor: 3.240

9.  Nanoscale Diblock copolymer micelles: characterizations and estimation of the effective diffusion coefficients of biomolecules release through cylindrical diffusion model.

Authors:  M Wahab Amjad; Mohd Cairul I Mohd Amin; Shalela M Mahali; Haliza Katas; Ismanizan Ismail; M Naeem Ul Hassan; Victor T Giam Chuang
Journal:  PLoS One       Date:  2014-08-18       Impact factor: 3.240

10.  RNA interference inhibits hepatitis E virus mRNA accumulation and protein synthesis in vitro.

Authors:  Fen Huang; Junfang Zhou; Zhibiao Yang; Li Cui; Wen Zhang; Congli Yuan; Shixing Yang; Jianguo Zhu; Xiuguo Hua
Journal:  Vet Microbiol       Date:  2009-11-06       Impact factor: 3.293
  10 in total

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