Literature DB >> 18724267

Host's response in otitis media: understanding genetic susceptibility.

Stavroula Ilia1, George N Goulielmos, George Samonis, Emmanouil Galanakis.   

Abstract

Increasing evidence is emerging on genetic factors affecting host's response to infection in the middle ear. This review summarizes current knowledge on the field and on the contribution of nonspecific barriers, innate, and adaptive immunity. Better understanding of susceptibility to this very common disease will facilitate identification of high-risk individuals and optimization of prevention and treatment.

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Mesh：

Year:  2008        PMID： 18724267     DOI： 10.1097/INF.0b013e318174e0b0

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN： 0891-3668            Impact factor:   2.129


  5 in total

1.  Higher serum levels of interleukin 10 occur at onset of acute otitis media caused by Streptococcus pneumoniae compared to Haemophilus influenzae and Moraxella catarrhalis.

Authors:  Keyi Liu; Ravinder Kaur; Anthony Almudevar; Michael E Pichichero
Journal:  Laryngoscope       Date:  2013-02-12       Impact factor: 3.325

2.  Otitis media: a genome-wide linkage scan with evidence of susceptibility loci within the 17q12 and 10q22.3 regions.

Authors:  Margaretha L Casselbrant; Ellen M Mandel; Jeesun Jung; Robert E Ferrell; Kathleen Tekely; Jin P Szatkiewicz; Amrita Ray; Daniel E Weeks
Journal:  BMC Med Genet       Date:  2009-09-03       Impact factor: 2.103

Review 3.  Panel 4: Recent advances in otitis media in molecular biology, biochemistry, genetics, and animal models.

Authors:  Jian-Dong Li; Ann Hermansson; Allen F Ryan; Lauren O Bakaletz; Steve D Brown; Michael T Cheeseman; Steven K Juhn; Timothy T K Jung; David J Lim; Jae Hyang Lim; Jizhen Lin; Sung-Kyun Moon; J Christopher Post
Journal:  Otolaryngol Head Neck Surg       Date:  2013-04       Impact factor: 3.497

4.  Toll-like receptors, cytokines & nitric oxide synthase in patients with otitis media with effusion.

Authors:  Ho Yun Lee; Ji Hyun Chung; Sun Kyu Lee; Jae Yong Byun; Young Il Kim; Seung Geun Yeo
Journal:  Indian J Med Res       Date:  2013-10       Impact factor: 2.375

5.  Copy number variation of the beta defensin gene cluster on chromosome 8p influences the bacterial microbiota within the nasopharynx of otitis-prone children.

Authors:  Eric A Jones; Anchasa Kananurak; Charles L Bevins; Edward J Hollox; Lauren O Bakaletz
Journal:  PLoS One       Date:  2014-05-27       Impact factor: 3.240
  5 in total

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