BACKGROUND: Because optical coherence tomography (OCT) requires balloon-occlusion to overcome image attenuation by blood, the present study investigated the safety and usefulness of a new non-occlusive technique. METHODS AND RESULTS: The 40 angina patients were assigned to the continuous-flushing method or the balloon-occlusion method group. The continuous-flushing method was superior for observing proximal lesions compared with the balloon-occlusion method (94% vs 55%, p=0.01). There were no differences between groups in the visible length and image quality. There were no major complications during OCT. CONCLUSIONS: The continuous-flushing method is safe and useful for OCT.
RCT Entities:
BACKGROUND: Because optical coherence tomography (OCT) requires balloon-occlusion to overcome image attenuation by blood, the present study investigated the safety and usefulness of a new non-occlusive technique. METHODS AND RESULTS: The 40 anginapatients were assigned to the continuous-flushing method or the balloon-occlusion method group. The continuous-flushing method was superior for observing proximal lesions compared with the balloon-occlusion method (94% vs 55%, p=0.01). There were no differences between groups in the visible length and image quality. There were no major complications during OCT. CONCLUSIONS: The continuous-flushing method is safe and useful for OCT.
Authors: Luis E Savastano; Quan Zhou; Arlene Smith; Karla Vega; Carlos Murga-Zamalloa; David Gordon; Jon McHugh; Lili Zhao; Michael Wang; Aditya Pandey; B Gregory Thompson; Jie Xu; Jifeng Zhang; Y Eugene Chen; Eric J Seibel; Thomas D Wang Journal: Nat Biomed Eng Date: 2017-02-10 Impact factor: 25.671