Literature DB >> 18722454

A general one-step synthesis of beta-nitronitriles.

James C Anderson1, Alexander J Blake, Matthew Mills, Paul D Ratcliffe.   

Abstract

The unusual beta-nitronitrile functionality was prepared by a simple one-step hydrocyanation of nitroalkenes. These compounds were shown to be precursors to monoprotected 1,3-diamines and 1,3-amino alcohols through the in situ formation of an alpha-cyano-aldenyde.

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Year:  2008        PMID： 18722454     DOI： 10.1021/ol801691c

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  6 in total

1.  Copper-Catalyzed Alkylation of Nitroalkanes with α-Bromonitriles: Synthesis of β-Cyanonitroalkanes.

Authors:  Kirk W Shimkin; Peter G Gildner; Donald A Watson
Journal:  Org Lett       Date:  2016-02-11       Impact factor: 6.005

2.  Asymmetric synthesis of diamine derivatives via sequential palladium and rhodium catalysis.

Authors:  Barry M Trost; Sushant Malhotra; David E Olson; Autumn Maruniak; J Du Bois
Journal:  J Am Chem Soc       Date:  2009-04-01       Impact factor: 15.419

3.  Asymmetric Addition of Cyanide to β-Nitroalkenes Catalysed by Chiral Salen Complexes of Titanium(IV) and Vanadium(V).

Authors:  Michael North; James M Watson
Journal:  ChemCatChem       Date:  2013-05-28       Impact factor: 5.686

4.  A versatile and efficient approach for the synthesis of chiral 1,3-nitroamines and 1,3-diamines via conjugate addition to new (S,E)-γ-aminated nitroalkenes derived from L-α-amino acids.

Authors:  Vera Lúcia Patrocinio Pereira; André Luiz da Silva Moura; Daniel Pais Pires Vieira; Leandro Lara de Carvalho; Eliz Regina Bueno Torres; Jeronimo da Silva Costa
Journal:  Beilstein J Org Chem       Date:  2013-04-30       Impact factor: 2.883

5.  Dinuclear PhosphoiminoBINOL-Pd Container for Malononitrile: Catalytic Asymmetric Double Mannich Reaction for Chiral 1,3-Diamine Synthesis.

Authors:  Takayoshi Arai; Katsuya Sato; Ayu Nakamura; Hiroki Makino; Hyuma Masu
Journal:  Sci Rep       Date:  2018-01-16       Impact factor: 4.379

Review 6.  The unveiling of the Warburg effect and the inscribed innovative approach to a radical non toxic anticancer therapy.

Authors:  Olivia Crociani; Ilaria Marzi; Maria Grazia Cipolleschi; Antonella Mannini; Massimo Contini; Massimo Olivotto
Journal:  Cell Cycle       Date:  2018-03-19       Impact factor: 4.534
  6 in total

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