BACKGROUND AND PURPOSE: Dysphagia is a serious complaint but frequently underreported. This paper assesses for oropharyngeal cancer (OPC) the relationship between the dose received by the swallowing structures, and the findings of a fiberoptic endoscopic evaluation of the swallowing process (FEES). MATERIALS AND METHODS: Between 2000 and 2005, 60 of 67 OPC patients local-regionally NED for at least one year following treatment responded to three types of QoL questionnaires; i.e. Performance Status Scales, EORTC H&N35, and M.D. Anderson Dysphagia Inventory. Twenty-four patients agreed to the FEES procedure. The main swallowing muscles were delineated, with the mean dose per muscle calculated using the original 3D CT-based treatment plans. Regression analysis was performed between FEES variables and the doses in the different swallowing muscles and the dysphagia related questionnaires. RESULTS: A significant relationship was found between the results of FEES and the mean dose in the superior constrictor muscle (SCM). Some of the subjective dysphagia complaints were significantly correlated with the FEES variables in this retrospectively study. CONCLUSION: A higher dose in the SCM generally results in worsening of the findings obtained by the FEES examination.
BACKGROUND AND PURPOSE:Dysphagia is a serious complaint but frequently underreported. This paper assesses for oropharyngeal cancer (OPC) the relationship between the dose received by the swallowing structures, and the findings of a fiberoptic endoscopic evaluation of the swallowing process (FEES). MATERIALS AND METHODS: Between 2000 and 2005, 60 of 67 OPC patients local-regionally NED for at least one year following treatment responded to three types of QoL questionnaires; i.e. Performance Status Scales, EORTC H&N35, and M.D. Anderson Dysphagia Inventory. Twenty-four patients agreed to the FEES procedure. The main swallowing muscles were delineated, with the mean dose per muscle calculated using the original 3D CT-based treatment plans. Regression analysis was performed between FEES variables and the doses in the different swallowing muscles and the dysphagia related questionnaires. RESULTS: A significant relationship was found between the results of FEES and the mean dose in the superior constrictor muscle (SCM). Some of the subjective dysphagia complaints were significantly correlated with the FEES variables in this retrospectively study. CONCLUSION: A higher dose in the SCM generally results in worsening of the findings obtained by the FEES examination.
Authors: Musaddiq J Awan; Abdallah S R Mohamed; Jan S Lewin; Charles A Baron; G Brandon Gunn; David I Rosenthal; F Christopher Holsinger; David L Schwartz; Clifton D Fuller; Katherine A Hutcheson Journal: Oral Oncol Date: 2014-06-03 Impact factor: 5.337
Authors: Mitchell Machtay; Jennifer Moughan; Andrew Farach; Elizabeth Martin-O'Meara; James Galvin; Adam S Garden; Randal S Weber; Jay S Cooper; Arlene Forastiere; K Kian Ang Journal: Int J Radiat Oncol Biol Phys Date: 2012-11-15 Impact factor: 7.038
Authors: David N Teguh; Peter C Levendag; Wendimagegn Ghidey; Kees van Montfort; Stefan L S Kwa Journal: Dysphagia Date: 2013-01-26 Impact factor: 3.438
Authors: Baoqing Li; Dan Li; Derick H Lau; D Gregory Farwell; Quang Luu; David M Rocke; Kathleen Newman; Jean Courquin; James A Purdy; Allen M Chen Journal: Radiat Oncol Date: 2009-11-12 Impact factor: 3.481