Literature DB >> 18721954

Corporeal grafting for severe hypospadias: a single institution experience with 3 techniques.

Jeffrey A Leslie1, Mark P Cain, Martin Kaefer, Kirstan K Meldrum, Rosalia Misseri, Richard C Rink.   

Abstract

PURPOSE: Correction of severe chordee by corporeal body grafting has been successfully performed using various grafts and biomaterials. We report a single institution comparison of our experience using small intestinal submucosa, tunica vaginalis and dermal grafts at stage 1 hypospadias repair.
MATERIALS AND METHODS: A retrospective chart review was performed of the records of all patients who underwent staged hypospadias repair from 1985 to 2006 with corporeal body grafting at stage 1 with small intestinal submucosa, tunica vaginalis or dermal grafts. Age at grafting, time between stages, residual chordee at stage 2 repair and the need for additional plication or chordee correction at stage 2 were recorded.
RESULTS: A total of 71 patients were identified with a median age of 10 months at stage 1 repair and a median of 7.6 months between stages 1 and 2 repair. Dermal grafts, tunica vaginalis and small intestinal submucosa grafts were used in 29, 21 and 20 patients, respectively. One patient received a combination of small intestinal submucosa and tunica vaginalis. None of the patients receiving tunica vaginalis graft required any further correction of chordee. One patient with a dermal graft and 1 receiving small intestinal submucosa required Nesbit plication at stage 2 repair for minor ventral chordee. One patients receiving small intestinal submucosa showed severe fibrosis at the graft site, requiring excision and repeat grafting with tunica vaginalis. This patient has been previously described. The 2 patients with small intestinal submucosa related complications had 4-ply grafts. We have seen no complications associated with 1-ply small intestinal submucosa. At limited followup we have not seen residual chordee after stage 2 repair.
CONCLUSIONS: In a large group of children requiring corporeal grafting for severe chordee we observed successful chordee correction with 1-ply small intestinal submucosa, tunica vaginalis or dermal grafts.

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Year:  2008        PMID: 18721954     DOI: 10.1016/j.juro.2008.03.091

Source DB:  PubMed          Journal:  J Urol        ISSN: 0022-5347            Impact factor:   7.450


  10 in total

1.  Tissue engineering in urology.

Authors:  Derek J Matoka; Earl Y Cheng
Journal:  Can Urol Assoc J       Date:  2009-10       Impact factor: 1.862

Review 2.  Update on tissue engineering in pediatric urology.

Authors:  Blake W Palmer; Bradley P Kropp
Journal:  Curr Urol Rep       Date:  2013-08       Impact factor: 3.092

3.  [Surgical trends in secondary hypospadias].

Authors:  M Musch; M Mosters; V Klevecka; D Kröpfl
Journal:  Urologe A       Date:  2011-05       Impact factor: 0.639

Review 4.  Correction of Residual Ventral Penile Curvature After Division of the Urethral Plate in the First Stage of a 2-Stage Proximal Hypospadias Repair.

Authors:  Bruce J Schlomer
Journal:  Curr Urol Rep       Date:  2017-02       Impact factor: 3.092

Review 5.  [Urethral reconstruction in patients with failed hypospadia repair].

Authors:  D Kröpfl; I Kunz
Journal:  Urologe A       Date:  2018-01       Impact factor: 0.639

6.  Management of Proximal Hypospadias with 2-Stage Repair: 20-Year Experience.

Authors:  Erin R McNamara; Anthony J Schaeffer; Tanya Logvinenko; Catherine Seager; Ilina Rosoklija; Caleb P Nelson; Alan B Retik; David A Diamond; Marc Cendron
Journal:  J Urol       Date:  2015-05-09       Impact factor: 7.450

Review 7.  A meta-analysis comparing dorsal plication and ventral lengthening for chordee correction during primary proximal hypospadias repair.

Authors:  Ramesh Babu; V V S Chandrasekharam
Journal:  Pediatr Surg Int       Date:  2022-01-19       Impact factor: 1.827

Review 8.  Proximal hypospadias: we aren't always keeping our promises.

Authors:  Christopher J Long; Douglas A Canning
Journal:  F1000Res       Date:  2016-09-26

9.  Can a graft be placed over a flap in complex hypospadias surgery? An experimental study in rabbits.

Authors:  Ricardo Marcondes de Mattos; Sérgio R R de Araújo; Juliany Gomes Quitzan; Bruno Leslie; Herick Bacelar; João Luiz Gomes Parizi; Gustavo Marconi Caetano Martins; Marcela Leal da Cruz; Antonio Macedo
Journal:  Int Braz J Urol       Date:  2016 Nov-Dec       Impact factor: 1.541

10.  Acellular dermal matrix graft for ventral corporal lengthening orthoplasty in 2-stage proximal hypospadias repair.

Authors:  Shaofeng Wu; Rong He; Jie Sun; Haiteng Zhao
Journal:  Transl Pediatr       Date:  2021-12
  10 in total

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