Literature DB >> 18721909

MIF in autoimmunity and novel therapeutic approaches.

Stanislava Stosic-Grujicic1, Ivana Stojanovic, Ferdinando Nicoletti.   

Abstract

Macrophage migration inhibitory factor (MIF) is a multipotent cytokine implicated in the pathogenesis of numerous inflammatory and autoimmune disorders. Since anti-cytokine therapy is considered to be a promising therapeutic strategy, selective targeting of MIF with either anti-MIF antibody or specific chemical MIF inhibitors might offer new therapeutic avenues for these disorders. Considering the unique relationship between MIF and glucocorticoids, therapeutic antagonism of MIF could also represent an effective approach for steroid-sparing therapies in patients with refractory autoimmune diseases.

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Year:  2008        PMID： 18721909     DOI： 10.1016/j.autrev.2008.07.037

Source DB:  PubMed          Journal:  Autoimmun Rev        ISSN： 1568-9972            Impact factor:   9.754


  23 in total

1.  Macrophage migration inhibitory factor deficiency protects pancreatic islets from cytokine-induced apoptosis in vitro.

Authors:  I Stojanovic; T Saksida; I Nikolic; F Nicoletti; S Stosic-Grujicic
Journal:  Clin Exp Immunol       Date:  2012-08       Impact factor: 4.330

2.  Serum level of macrophage migration inhibitory factor (MIF) in Egyptians with alopecia areata and its relation to the clinical severity of the disease.

Authors:  Doreen Nazeih Assaad Younan; Naglaa Agamia; Adel Elshafei; Nancy Ebeid
Journal:  J Clin Lab Anal       Date:  2014-03-28       Impact factor: 2.352

Review 3.  Glucocorticoid sensitivity in health and disease.

Authors:  Rogier A Quax; Laura Manenschijn; Jan W Koper; Johanna M Hazes; Steven W J Lamberts; Elisabeth F C van Rossum; Richard A Feelders
Journal:  Nat Rev Endocrinol       Date:  2013-10-01       Impact factor: 43.330

Review 4.  Beta cell function: the role of macrophage migration inhibitory factor.

Authors:  Ivana Stojanovic; Tamara Saksida; Stanislava Stosic-Grujicic
Journal:  Immunol Res       Date:  2012-04       Impact factor: 2.829

5.  Macrophage migration inhibitory factor-knockout mice are long lived and respond to caloric restriction.

Authors:  James M Harper; J Erby Wilkinson; Richard A Miller
Journal:  FASEB J       Date:  2010-03-10       Impact factor: 5.191

6.  Inhibition of macrophage migration inhibitory factor reduces endometriotic implant size in mice with experimentally induced disease.

Authors:  Warren B Nothnick; Arlene Colvin; Kai Fan Cheng; Yousef Al-Abed
Journal:  J Endometr       Date:  2011-09-30

7.  Neutralization of macrophage migration inhibitory factor (MIF) by fully human antibodies correlates with their specificity for the β-sheet structure of MIF.

Authors:  Randolf J Kerschbaumer; Manfred Rieger; Dirk Völkel; Didier Le Roy; Thierry Roger; Jurate Garbaraviciene; Wolf-Henning Boehncke; Jürgen Müllberg; Rene M Hoet; Clive R Wood; Gerhard Antoine; Michael Thiele; Helga Savidis-Dacho; Michael Dockal; Hartmut Ehrlich; Thierry Calandra; Friedrich Scheiflinger
Journal:  J Biol Chem       Date:  2012-01-11       Impact factor: 5.157

8.  A Macrophage Migration Inhibitory Factor Polymorphism Is Associated with Autoimmune Hepatitis Severity in US and Japanese Patients.

Authors:  David N Assis; Hiroki Takahashi; Lin Leng; Mikio Zeniya; James L Boyer; Richard Bucala
Journal:  Dig Dis Sci       Date:  2016-10-01       Impact factor: 3.199

9.  Macrophage migration inhibitory factor is an endogenous regulator of stress-induced extramedullary erythropoiesis.

Authors:  Sanja Vignjević Petrinović; Mirela Budeč; Dragana Marković; Mirjana Gotić; Olivera Mitrović Ajtić; Slavko Mojsilović; Stanislava Stošić-Grujičić; Milan Ivanov; Gordana Jovčić; Vladan Čokić
Journal:  Histochem Cell Biol       Date:  2016-04-30       Impact factor: 4.304

10.  Modulating mammary tumor growth, metastasis and immunosuppression by siRNA-induced MIF reduction in tumor microenvironment.

Authors:  M Zhang; L Yan; J A Kim
Journal:  Cancer Gene Ther       Date:  2015-09-25       Impact factor: 5.987
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