Literature DB >> 18721592

Spontaneous pneumomediastinum: a comparative study and review of the literature.

Manuel Caceres1, Syed Z Ali, Rebecca Braud, Darryl Weiman, H Edward Garrett.   

Abstract

BACKGROUND: Spontaneous pneumomediastinum (SPM) is an unusual occurrence with few cases reported. It is seen after intrathoracic pressure changes leading to alveolar rupture and dissection of air along the tracheobronchial tree. This study was undertaken to provide a thorough clinical and radiologic analysis of this patient population.
METHODS: A retrospective comparative analysis was performed on patients with SPM over 12 years. Patient demographics, clinical presentation, and radiographic and diagnostic studies were recorded. A clinical and radiologic comparison was performed with secondary pneumomediastinum.
RESULTS: Seventy-four patients were identified with a diagnosis of pneumomediastinum. A total of 28 patients with SPM were identified. The major initial complaints were chest pain (54%), shortness of breath (39%), and subcutaneous emphysema (32%). The main triggering events were emesis (36%) and asthma flare-ups (21%). No apparent triggering event was noted in 21% of patients. Chest radiograph was diagnostic in 69%; computed tomography was required in 31%. Esophagram, esophagoscopy, and bronchoscopy were performed on an individual basis and were invariably negative. When compared with secondary pneumomediastinum, SPM is more likely to be discovered by chest radiography, has a lower incidence of pneumothorax and pleural effusion, requires a shorter hospital stay, and has no associated mortality.
CONCLUSIONS: Spontaneous pneumomediastinum is a benign condition that often presents with chest pain or dyspnea. It can develop without a triggering event and with no findings on chest radiography. Treatment is expectant and recurrence is low. Secondary causes must be ruled out to avoid an unfavorable outcome.

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Year:  2008        PMID: 18721592     DOI: 10.1016/j.athoracsur.2008.04.067

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  62 in total

1.  Spontaneous pneumomediastinum associated with sex.

Authors:  Sam Flatman; Edwin Morrison; Maqsood Elahi
Journal:  J Radiol Case Rep       Date:  2010-04-01

2.  Spontaneous pneumomediastinum due to achalasia: an unusual but benign cause.

Authors:  Ramin Javan; Richard Duszak; Keith Tonkin
Journal:  J Radiol Case Rep       Date:  2010-11-01

3.  Pneumomediastinum and subcutaneous emphysema in a cat associated with necrotizing bronchopneumonia caused by feline herpesvirus-1.

Authors:  Sofie Maes; Bart Van Goethem; Jimmy Saunders; Dominique Binst; Koen Chiers; Richard Ducatelle
Journal:  Can Vet J       Date:  2011-10       Impact factor: 1.008

4.  Pneumomediastinum and subcutaneous emphysema associated with pandemic (H1N1) influenza in three children.

Authors:  Sharmila Udupa; Tahir Hameed; Tom Kovesi
Journal:  CMAJ       Date:  2010-12-06       Impact factor: 8.262

5.  Spontaneous pneumomediastinum.

Authors:  Ankush Gupta; Imran Rizvi; Vijay Kumar Srivastava; Jyotindu Debnath; B N Kapur; V N Khanna; Atiya Aziz
Journal:  Med J Armed Forces India       Date:  2013-06-06

6.  Clinical experience of spontaneous pneumomediastinum: diagnosis and treatment.

Authors:  Kyung Soo Kim; Hyun Woo Jeon; Youngkyu Moon; Young Du Kim; Myeong Im Ahn; Jae Kil Park; Keon Hyun Jo
Journal:  J Thorac Dis       Date:  2015-10       Impact factor: 2.895

7.  Analysis of Patients with Spontaneous Pneumomediastinum.

Authors:  Muharrem Çakmak; Melih Yüksel; Mehmet Nail Kandemir
Journal:  Turk Thorac J       Date:  2016-07-01

8.  Spontaneous pneumomediastinum.

Authors:  Emmet E McGrath; Zoe Blades; Chris Barber
Journal:  CMAJ       Date:  2009-09-14       Impact factor: 8.262

9.  Spontaneous pneumomediastinum: a rare presentation of diabetic ketoacidosis in a pregnant woman.

Authors:  Leonie Speksnijder; Johannes J Duvekot; Erik J J Duschek; Max C W Jebbink; Henk A Bremer
Journal:  Obstet Med       Date:  2010-12-03

10.  Newly formed cystic lesions for the development of pneumomediastinum in Pneumocystis jirovecii pneumonia.

Authors:  Ju-Yeon Cho; Dong-Min Kim; Yong Eun Kwon; Sung Ho Yoon; Seung Il Lee
Journal:  BMC Infect Dis       Date:  2009-10-18       Impact factor: 3.090

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