Yoshiyuki Takami1, Hiroshi Masumoto. 1. Department of Cardiovascular Surgery, Nagoya Daini Red Cross Hospital, Japan. takami@nagoya2.jrc.or.jp
Abstract
BACKGROUND: We investigated hemodynamic effects of intra-aortic balloon pumping (IABP) in in-situ and aorta-coronary (A-C) grafts during coronary artery bypass grafting (CABG). METHODS: One hundred seventy-two grafts, including 84 in-situ left internal thoracic arteries (LITAs), were examined intraoperatively with a transit-time flowmeter in 84 patients who had prophylactic IABP. The following measurements were obtained for each graft during off-IABP and on-IABP: mean flow, maximal flow, pulsatility index, and diastolic filling index. Coronary angiograms were performed 14 +/- 5 days after coronary artery bypass graft surgery to verify the patency of the grafts. RESULTS: All measurements of 163 patent and measurable grafts were significantly increased with IABP: mean flow 46 +/- 27 to 51 +/- 29 mL/min; maximal flow 87 +/- 52 to 121 +/- 69 mL/min; pulsatility index 2.2 +/- 1.4 to 3.1 +/- 1.4; and diastolic filling index 64% +/- 8% to 71% +/- 9% (p < 0.001). Among them, the degrees of increase of mean flow and diastolic filling index were significantly different between the in-situ LITAs and A-C grafts (mean flow 18% +/- 20% versus 10% +/- 15%, p = 0.04; diastolic filling index 10% +/- 8% versus 14% +/- 9%, p = 0.04). CONCLUSIONS: IABP assist significantly increases graft flow and also diastolic components of flow. The degree of increase is greater in the in-situ LITA supplying the left anterior descending artery than in A-C grafts anastomosed to other coronary arteries. IABP increases the diastolic component more in A-C grafts than in in-situ LITAs, probably because of different flow characteristics of the two grafts.
BACKGROUND: We investigated hemodynamic effects of intra-aortic balloon pumping (IABP) in in-situ and aorta-coronary (A-C) grafts during coronary artery bypass grafting (CABG). METHODS: One hundred seventy-two grafts, including 84 in-situ left internal thoracic arteries (LITAs), were examined intraoperatively with a transit-time flowmeter in 84 patients who had prophylactic IABP. The following measurements were obtained for each graft during off-IABP and on-IABP: mean flow, maximal flow, pulsatility index, and diastolic filling index. Coronary angiograms were performed 14 +/- 5 days after coronary artery bypass graft surgery to verify the patency of the grafts. RESULTS: All measurements of 163 patent and measurable grafts were significantly increased with IABP: mean flow 46 +/- 27 to 51 +/- 29 mL/min; maximal flow 87 +/- 52 to 121 +/- 69 mL/min; pulsatility index 2.2 +/- 1.4 to 3.1 +/- 1.4; and diastolic filling index 64% +/- 8% to 71% +/- 9% (p < 0.001). Among them, the degrees of increase of mean flow and diastolic filling index were significantly different between the in-situ LITAs and A-C grafts (mean flow 18% +/- 20% versus 10% +/- 15%, p = 0.04; diastolic filling index 10% +/- 8% versus 14% +/- 9%, p = 0.04). CONCLUSIONS: IABP assist significantly increases graft flow and also diastolic components of flow. The degree of increase is greater in the in-situ LITA supplying the left anterior descending artery than in A-C grafts anastomosed to other coronary arteries. IABP increases the diastolic component more in A-C grafts than in in-situ LITAs, probably because of different flow characteristics of the two grafts.
Authors: Christian Jung; Christoph Rödiger; Michael Fritzenwanger; Julia Schumm; Alexander Lauten; Hans R Figulla; Markus Ferrari Journal: Clin Res Cardiol Date: 2009-04-15 Impact factor: 5.460