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Literature DB >> 187215

Coupling of spin, substrate, and redox equilibria in cytochrome P450.

S G Sligar.

Abstract

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Year: 1976 PMID： 187215 DOI： 10.1021/bi00669a029

Source DB: PubMed Journal: Biochemistry ISSN： 0006-2960 Impact factor: 3.162

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62 in total

1. Spring-loading the active site of cytochrome P450cam.

Authors: Marina Dang; Susan Sondej Pochapsky; Thomas C Pochapsky
Journal: Metallomics Date: 2010-12-24 Impact factor: 4.526

2. Conformational transitions and redox potential shifts of cytochrome P450 induced by immobilization.

Authors: Smilja Todorovic; Christiane Jung; Peter Hildebrandt; Daniel H Murgida
Journal: J Biol Inorg Chem Date: 2005-12-03 Impact factor: 3.358

3. Conformational equilibrium of cytochrome P450 BM-3 complexed with N-palmitoylglycine: a replica exchange molecular dynamics study.

Authors: Krishna Pratap Ravindranathan; Emilio Gallicchio; Richard A Friesner; Ann E McDermott; Ronald M Levy
Journal: J Am Chem Soc Date: 2006-05-03 Impact factor: 15.419

4. Redox potential control by drug binding to cytochrome P450 3A4.

Authors: Aditi Das; Yelena V Grinkova; Stephen G Sligar
Journal: J Am Chem Soc Date: 2007-10-19 Impact factor: 15.419

5. Identification, characterization, and azole-binding properties of Mycobacterium smegmatis CYP164A2, a homolog of ML2088, the sole cytochrome P450 gene of Mycobacterium leprae.

Authors: Andrew G S Warrilow; Colin J Jackson; Josie E Parker; Timothy H Marczylo; Diane E Kelly; David C Lamb; Steven L Kelly
Journal: Antimicrob Agents Chemother Date: 2008-12-15 Impact factor: 5.191

10. Inhibition of CYP2B4 by the mechanism-based inhibitor 2-ethynylnaphthalene: inhibitory potential of 2EN is dependent on the size of the substrate.

Authors: Dongmei Cheng; James R Reed; Danni Harris; Wayne L Backes
Journal: Arch Biochem Biophys Date: 2007-04-09 Impact factor: 4.013

Coupling of spin, substrate, and redox equilibria in cytochrome P450.

1. Spring-loading the active site of cytochrome P450cam.

2. Conformational transitions and redox potential shifts of cytochrome P450 induced by immobilization.

3. Conformational equilibrium of cytochrome P450 BM-3 complexed with N-palmitoylglycine: a replica exchange molecular dynamics study.

4. Redox potential control by drug binding to cytochrome P450 3A4.

5. Identification, characterization, and azole-binding properties of Mycobacterium smegmatis CYP164A2, a homolog of ML2088, the sole cytochrome P450 gene of Mycobacterium leprae.

Review 6. Correlating structure and function of drug-metabolizing enzymes: progress and ongoing challenges.

7. Steroid bioconjugation to a CYP3A4 allosteric site and its effect on substrate binding and coupling efficiency.

8. CYP153A6, a soluble P450 oxygenase catalyzing terminal-alkane hydroxylation.

9. Mixing apples and oranges: Analysis of heterotropic cooperativity in cytochrome P450 3A4.

10. Inhibition of CYP2B4 by the mechanism-based inhibitor 2-ethynylnaphthalene: inhibitory potential of 2EN is dependent on the size of the substrate.