Literature DB >> 18718619

Antibacterial activity of halogenated sesquiterpenes from Malaysian Laurencia spp.

Charles Santhanaraju Vairappan1, Minoru Suzuki, Takahiro Ishii, Tatsufumi Okino, Tsuyoshi Abe, Michio Masuda.   

Abstract

During our studies on Malaysian Laurencia species, brominated metabolites, tiomanene, acetylmajapolene B, and acetylmajapolene A were isolated from an unrecorded species collected at Pulau Tioman, Pahang along with known majapolene B and majapolene A. Acetylmajapolene A was a mixture of diastereomers as in the case of majapolene A. Tiomanene may be a plausible precursor for acetylmajapolenes B and A. In addition, three known halogenated sesquiterpenes and two known halogenated C(15) acetogenins were found from other two unrecorded species collected at Pulau Karah, Terengganu and Pulau Nyireh, Terengganu, respectively. Some of these halogenated metabolites showed moderate antibacterial activity against some marine bacteria.

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Year:  2008        PMID: 18718619     DOI: 10.1016/j.phytochem.2008.06.015

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  12 in total

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2.  Antibacterial activities of a new brominated diterpene from Borneon Laurencia spp.

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