Literature DB >> 18715731

[Systematic family screening in case of infant pertussis].

E Bosdure1, J Raymond, C Cosnes-Lambe, B Rheinardt, M-J El Hajje, J-B Armengaud, F Moulin, M Chalumeau, H Reglier-Poupet, C Poyart, D Gendrel.   

Abstract

The origin of contamination in pertussis of young infants is generally the close relatives. From 2000 to 2004, only serology and culture were available in our hospital. The families of 16 young infants (age below one year) hospitalized for pertussis were screened using serological tests: 21/48 contacts were positive. After 2004, PCR was available for exploration of index cases and families: 35/85 contacts were positive. Of the mothers tested 23/46 were positive compared to 14/41 fathers. Only one parent presented with a typical paroxystic pertussis cough, 60% presented with a nonparoxystic cough having lasted for more than five days and 40% of positive adults did not present with cough. Despite official recommendations, none of these young parents had received an antipertussis booster vaccination. This study shows the high frequency of atypical or nonsymptomatic pertussis in adults in the close family of infected young infants. These adults contribute to spreading the disease.

Entities:  

Mesh:

Year:  2008        PMID: 18715731     DOI: 10.1016/j.medmal.2008.06.026

Source DB:  PubMed          Journal:  Med Mal Infect        ISSN: 0399-077X            Impact factor:   2.152


  1 in total

1.  Improving adherence rates to a cocooning program: a pilot experience in Italy.

Authors:  Andrea Simonetti; Ida Martini; Gennaro Bonomo; Raffaele D'Avino; Paolo Puggina; Ugo Vairo; Pasquale Piscopo; Federico Marchetti
Journal:  Hum Vaccin Immunother       Date:  2013-01-31       Impact factor: 3.452

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.