OBJECTIVE: To assess whether application of cocoa butter lotion reduces the development of striae gravidarum (SG). DESIGN: Multicentre, double-blind, randomised and placebo-controlled trial. SETTING: Beirut and Tripoli, Lebanon. POPULATION: Nulliparous women presenting for prenatal care. METHODS:Nulliparous women presenting in the first trimester were randomly assigned to receive a lotion containing cocoa butter or a placebo lotion. Women were instructed to apply the assigned lotion daily until delivery. MAIN OUTCOME MEASURE: The development of striae over the abdomen, breasts and thighs postpartum. RESULTS: Of 210 women enrolled, 175 (83%) completed the study. Ninety-one women received the study lotion and 84 received theplacebo. There was no difference in the development of SG (45.1% versus 48.8%; P = 0.730) or the severity of SG between cases and controls. The results did not change when presence of stretch marks at enrolment or compliance with the regimen were taken into account. CONCLUSION: Topical application of a lotion containing cocoa butter does not appear to reduce the likelihood of developing striae gravidarum.
RCT Entities:
OBJECTIVE: To assess whether application of cocoabutter lotion reduces the development of striae gravidarum (SG). DESIGN: Multicentre, double-blind, randomised and placebo-controlled trial. SETTING: Beirut and Tripoli, Lebanon. POPULATION: Nulliparous women presenting for prenatal care. METHODS: Nulliparous women presenting in the first trimester were randomly assigned to receive a lotion containing cocoabutter or a placebo lotion. Women were instructed to apply the assigned lotion daily until delivery. MAIN OUTCOME MEASURE: The development of striae over the abdomen, breasts and thighs postpartum. RESULTS: Of 210 women enrolled, 175 (83%) completed the study. Ninety-one women received the study lotion and 84 received the placebo. There was no difference in the development of SG (45.1% versus 48.8%; P = 0.730) or the severity of SG between cases and controls. The results did not change when presence of stretch marks at enrolment or compliance with the regimen were taken into account. CONCLUSION: Topical application of a lotion containing cocoabutter does not appear to reduce the likelihood of developing striae gravidarum.