Literature DB >> 18713746

Endogenous functions of the aryl hydrocarbon receptor (AHR): intersection of cytochrome P450 1 (CYP1)-metabolized eicosanoids and AHR biology.

Daniel W Nebert1, Christopher L Karp.   

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Year:  2008        PMID： 18713746      PMCID： PMC2606007          DOI： 10.1074/jbc.R800053200

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


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4.  Microarray analysis of the AHR system: tissue-specific flexibility in signal and target genes.

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Journal:  Nat Rev Cancer       Date:  2006-12       Impact factor: 60.716

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Review 9.  Structure, biochemistry and biology of hepoxilins: an update.

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1.  Aryl hydrocarbon receptor ligand 2,3,7,8-tetrachlorodibenzo-p-dioxin enhances liver damage in bile duct-ligated mice.

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2.  Contributions of the three CYP1 monooxygenases to pro-inflammatory and inflammation-resolution lipid mediator pathways.

Authors:  Senad Divanovic; Jesmond Dalli; Lucia F Jorge-Nebert; Christopher L Karp; Charles N Serhan; Daniel W Nebert; Leah M Flick; Marina Gálvez-Peralta; Nicholas D Boespflug; Traci E Stankiewicz; Jonathan M Fitzgerald; Maheshika Somarathna
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3.  Mammalian cell-line based toxicological evaluation of paper mill black liquor treated in a soil microcosm by indigenous alkalo-tolerant Bacillus sp.

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6.  Attenuation of antigenic immunogenicity by kynurenine, a novel suppressive adjuvant.

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7.  Generation of a 'humanized' hCYP1A1_1A2_Cyp1a1/1a2(-/-)_Ahrd mouse line harboring the poor-affinity aryl hydrocarbon receptor.

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9.  Dynamic zebrafish interactome reveals transcriptional mechanisms of dioxin toxicity.

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10.  Knock-in mouse lines expressing either mitochondrial or microsomal CYP1A1: differing responses to dietary benzo[a]pyrene as proof of principle.

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