Literature DB >> 18713569

Novel therapeutic targets in neurodegenerative diseases: lessons from amyotrophic lateral sclerosis.

Stanley H Appel1, David R Beers, Jenny S Henkel, Weihua Zhao.   

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Year:  2008        PMID： 18713569     DOI： 10.1007/s11910-008-0054-6

Source DB:  PubMed          Journal:  Curr Neurol Neurosci Rep        ISSN： 1528-4042            Impact factor:   5.081


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  17 in total

1.  The chemokine MCP-1 and the dendritic and myeloid cells it attracts are increased in the mSOD1 mouse model of ALS.

Authors:  Jenny S Henkel; David R Beers; László Siklós; Stanley H Appel
Journal:  Mol Cell Neurosci       Date:  2005-12-05       Impact factor: 4.314

2.  Onset and progression in inherited ALS determined by motor neurons and microglia.

Authors:  Séverine Boillée; Koji Yamanaka; Christian S Lobsiger; Neal G Copeland; Nancy A Jenkins; George Kassiotis; George Kollias; Don W Cleveland
Journal:  Science       Date:  2006-06-02       Impact factor: 47.728

3.  Therapeutic effects of immunization with mutant superoxide dismutase in mice models of amyotrophic lateral sclerosis.

Authors:  Makoto Urushitani; Samer Abou Ezzi; Jean-Pierre Julien
Journal:  Proc Natl Acad Sci U S A       Date:  2007-02-02       Impact factor: 11.205

4.  The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice.

Authors:  Du-Chu Wu; Diane Bérangère Ré; Makiko Nagai; Harry Ischiropoulos; Serge Przedborski
Journal:  Proc Natl Acad Sci U S A       Date:  2006-07-28       Impact factor: 11.205

5.  Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS.

Authors:  Cédric Raoul; Toufik Abbas-Terki; Jean-Charles Bensadoun; Sandrine Guillot; Georg Haase; Jolanta Szulc; Christopher E Henderson; Patrick Aebischer
Journal:  Nat Med       Date:  2005-03-13       Impact factor: 53.440

6.  An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS.

Authors:  Rishi Rakhit; Janice Robertson; Christine Vande Velde; Patrick Horne; Deborah M Ruth; Jennifer Griffin; Don W Cleveland; Neil R Cashman; Avijit Chakrabartty
Journal:  Nat Med       Date:  2007-05-07       Impact factor: 53.440

7.  SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model.

Authors:  Maged M Harraz; Jennifer J Marden; Weihong Zhou; Yulong Zhang; Aislinn Williams; Victor S Sharov; Kathryn Nelson; Meihui Luo; Henry Paulson; Christian Schöneich; John F Engelhardt
Journal:  J Clin Invest       Date:  2008-02       Impact factor: 14.808

8.  Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria.

Authors:  Jian Liu; Concepción Lillo; P Andreas Jonsson; Christine Vande Velde; Christopher M Ward; Timothy M Miller; Jamuna R Subramaniam; Jeffery D Rothstein; Stefan Marklund; Peter M Andersen; Thomas Brännström; Ole Gredal; Philip C Wong; David S Williams; Don W Cleveland
Journal:  Neuron       Date:  2004-07-08       Impact factor: 17.173

9.  Mutant SOD1(G93A) microglia are more neurotoxic relative to wild-type microglia.

Authors:  Qin Xiao; Weihua Zhao; David R Beers; Albert A Yen; Wenjie Xie; Jenny S Henkel; Stanley H Appel
Journal:  J Neurochem       Date:  2007-06-07       Impact factor: 5.372

10.  Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis.

Authors:  Arie Gruzman; William L Wood; Evgenia Alpert; M Dharma Prasad; Robert G Miller; Jeffery D Rothstein; Robert Bowser; Ronald Hamilton; Troy D Wood; Don W Cleveland; Vishwanath R Lingappa; Jian Liu
Journal:  Proc Natl Acad Sci U S A       Date:  2007-07-16       Impact factor: 11.205
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  1 in total

Review 1.  CD 4+ T cells in the pathobiology of neurodegenerative disorders.

Authors:  Xiuyan Huang; Ashley D Reynolds; R Lee Mosley; Howard E Gendelman
Journal:  J Neuroimmunol       Date:  2009-05-12       Impact factor: 3.478
  1 in total

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