Literature DB >> 18713427

Two new triterpenoid saponins from Gymnema sylvestre.

Xu-Min Zhu1, Ping Xie, Ying-Tong Di, Shu-Lin Peng, Li-Sheng Ding, Ming-Kui Wang.   

Abstract

Two new oleanane-type triterpenoid saponins, gymnemoside-W1 and W2, together with seven known compounds were isolated from the leaves of Gymnema sylvestre R. Br. By means of spectral and chemical analysis, the structures of the new compounds were elucidated as 16 beta-hydroxyl olean-12-en-3-O-[beta-D-glucopyranosyl (1-->6)-beta-D-glucopyranosyl]-28-O-beta-D-glucopyranoside(1) and 16 beta,21 beta,28-trihydroxyl-olean-12-ene-3-O-glucoronopyranoside (2). The EtOH/H(2)O extracts of this plant were shown to be able to inhibit glucose absorption in rats.

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Year:  2008        PMID： 18713427     DOI： 10.1111/j.1744-7909.2008.00661.x

Source DB:  PubMed          Journal:  J Integr Plant Biol        ISSN： 1672-9072            Impact factor:   7.061


  8 in total

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2.  Biolarvicidal compound gymnemagenol isolated from leaf extract of miracle fruit plant, Gymnema sylvestre (Retz) Schult against malaria and filariasis vectors.

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3.  In vitro Inhibitory Effect of Gymnema sylvestre Extracts and Total Gymnemic Acids Fraction on Select Cytochrome P450 Activities in Rat Liver Microsomes.

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5.  Treating type 2 diabetes mellitus with traditional chinese and Indian medicinal herbs.

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6.  Inhibitory Effects of Gymnema (Gymnema sylvestre) Leaves on Tumour Promotion in Two-Stage Mouse Skin Carcinogenesis.

Authors:  Ken Yasukawa; Sakiko Okuda; Yasuhito Nobushi
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7.  Five New Pregnane Glycosides from Gymnema sylvestre and Their α-Glucosidase and α-Amylase Inhibitory Activities.

Authors:  Phan Van Kiem; Duong Thi Hai Yen; Nguyen Van Hung; Nguyen Xuan Nhiem; Bui Huu Tai; Do Thi Trang; Pham Hai Yen; Tran Minh Ngoc; Chau Van Minh; SeonJu Park; Jae Hyuk Lee; Sun Yeou Kim; Seung Hyun Kim
Journal:  Molecules       Date:  2020-05-28       Impact factor: 4.411

8.  Characterization and evaluation of mycosterol secreted from endophytic strain of Gymnema sylvestre for inhibition of α-glucosidase activity.

Authors:  Amit Ranjan; Rajesh Kumar Singh; Saumya Khare; Ruchita Tripathi; Rajesh Kumar Pandey; Anurag Kumar Singh; Vibhav Gautam; Jyoti Shankar Tripathi; Santosh Kumar Singh
Journal:  Sci Rep       Date:  2019-11-21       Impact factor: 4.379
  8 in total

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