AIM: To determine quality of life (QOL) in patients with mild cognitive impairment (MCI) compared to normal subjects and to investigate the impact of demographic factors on QOL. METHODS: There were 122 participants aged 50 and over, diagnosed with MCI (n = 85) or normal (n = 37) recruited from a community-based setting in Bangkok. The Thai version of the World Health Organization Quality of Life (WHOQOL-BREF-THAI) was used to assess the QOL in the subjects. RESULTS: The MCI patients had significantly lower psychological QOL compared to normal subjects. The MCI patients with low education had poorer total QOL scores, and patients with poor financial status had poorer psychological QOL scores and total QOL scores. The MCI patients who lived alone had poorer social relationship QOL. There were correlations between the Thai version of Geriatric Depression Scale (TGDS) and physical QOL, TGDS and psychological QOL, and TGDS and total QOL scores. The depression subscale of the Neuropsychiatric Inventory had negative correlation with physical and psychological QOL. CONCLUSION: The MCI patients had poorer psychological QOL than normal subjects. Low education, poor financial status, living alone and depressive symptoms had an influence on the quality of life.
AIM: To determine quality of life (QOL) in patients with mild cognitive impairment (MCI) compared to normal subjects and to investigate the impact of demographic factors on QOL. METHODS: There were 122 participants aged 50 and over, diagnosed with MCI (n = 85) or normal (n = 37) recruited from a community-based setting in Bangkok. The Thai version of the World Health Organization Quality of Life (WHOQOL-BREF-THAI) was used to assess the QOL in the subjects. RESULTS: The MCI patients had significantly lower psychological QOL compared to normal subjects. The MCI patients with low education had poorer total QOL scores, and patients with poor financial status had poorer psychological QOL scores and total QOL scores. The MCI patients who lived alone had poorer social relationship QOL. There were correlations between the Thai version of Geriatric Depression Scale (TGDS) and physical QOL, TGDS and psychological QOL, and TGDS and total QOL scores. The depression subscale of the Neuropsychiatric Inventory had negative correlation with physical and psychological QOL. CONCLUSION: The MCI patients had poorer psychological QOL than normal subjects. Low education, poor financial status, living alone and depressive symptoms had an influence on the quality of life.
Authors: Lilah M Besser; Daniel A Rodriguez; Noreen McDonald; Walter A Kukull; Annette L Fitzpatrick; Stephen R Rapp; Teresa Seeman Journal: Soc Sci Med Date: 2018-01-09 Impact factor: 4.634
Authors: Elisabeth M Weiss; Ilona Papousek; Andreas Fink; Theresa Matt; Josef Marksteiner; Eberhard A Deisenhammer Journal: Neuropsychiatr Date: 2012-07-27
Authors: R Scott Mackin; Philip Insel; Duygu Tosun; Susanne G Mueller; Norbert Schuff; Diana Truran-Sacrey; Sky T Raptentsetsang; Jun-Young Lee; Clifford R Jack; Paul S Aisen; Ronald C Petersen; Michael W Weiner Journal: Am J Geriatr Psychiatry Date: 2013-02-06 Impact factor: 4.105
Authors: Melanie T Gentry; Maria I Lapid; Jeremy Syrjanen; Kendrick Calvert; Samantha Hughes; Danielle Brushaber; Walter Kremers; Jessica Bove; Patrick Brannelly; Giovanni Coppola; Christina Dheel; Bradley Dickerson; Susan Dickinson; Kelley Faber; Julie Fields; Jamie Fong; Tatiana Foroud; Leah Forsberg; Ralitza Gavrilova; Deb Gearhart; Nupur Ghoshal; Jill Goldman; Jonathan Graff-Radford; Neill Graff-Radford; Murray Grossman; Dana Haley; Hilary Heuer; Ging-Yuek Hsiung; Edward Huey; David Irwin; David Jones; Lynne Jones; Kejal Kantarci; Anna Karydas; David Knopman; John Kornak; Joel Kramer; Walter Kukull; Diane Lucente; Codrin Lungu; Ian Mackenzie; Masood Manoochehri; Scott McGinnis; Bruce Miller; Rodney Pearlman; Len Petrucelli; Madeline Potter; Rosa Rademakers; Eliana Marisa Ramos; Katherine Rankin; Katya Rascovsky; Pheth Sengdy; Leslie Shaw; Nadine Tatton; Joanne Taylor; Arthur Toga; John Trojanowski; Sandra Weintraub; Bonnie Wong; Zbigniew Wszolek; Bradley F Boeve; Adam Boxer; Howard Rosen Journal: Alzheimers Dement Date: 2020-07-13 Impact factor: 21.566