Literature DB >> 18709257

Changes in pulmonary function after surgical treatment of congenital heart disease with pulmonary hyperflow.

Lilian Goraieb1, Ulisses Alexandre Croti, Suzana Renata Perez Orrico, Omar Yesid Prieto Rincon, Domingo Marcolino Braile.   

Abstract

BACKGROUND: Analysis of pulmonary status of pediatric patients in the postoperative phase of cardiac surgery.
OBJECTIVE: To assess pulmonary compliance and airway resistance in patients with congenital heart disease and pulmonary hyperflow submitted to surgical treatment with the use of extracorporeal circulation.
METHODS: Thirty-five patients were evaluated during surgery with measurements of static compliance and airway resistance at four different timepoints. Pulmonary measurements were performed non-invasively using end-inspiratory airway occlusion and specific mathematical formulas. The variables examined and related to pulmonary changes were: preoperative - age, weight, and relationship between systemic and pulmonary blood flow; intraoperative - perfusion times, anoxia times and minimum temperature; postoperative - time on mechanical ventilation and length of stay in the intensive care unit.
RESULTS: Pulmonary compliance in all patients had an immediate and significant increase (P<0.001) at the end of surgery. Patients older than 30 months experienced a greater increase (P=0.0004). Those with more than 10 kg also had a greater increase (P=0.0006). In patients on extracorporeal circulation for more than 50 minutes, the increase in pulmonary compliance took longer to occur (P=0.04). Airway resistance was not significantly changed at the end of surgery (P=0.393).
CONCLUSION: All patients experienced improved pulmonary compliance at the end of surgery, and this was significantly influenced by age, weight and time on extracorporeal circulation. Airway resistance, however, was not changed.

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Year:  2008        PMID: 18709257     DOI: 10.1590/s0066-782x2008001400003

Source DB:  PubMed          Journal:  Arq Bras Cardiol        ISSN: 0066-782X            Impact factor:   2.000


  1 in total

1.  Pulmonary functions before and after pediatric cardiac surgery.

Authors:  Hala Agha; Fatma El Heinady; Mona El Falaky; Alae Sobih
Journal:  Pediatr Cardiol       Date:  2013-10-30       Impact factor: 1.655

  1 in total

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