Literature DB >> 18709024

Multiple effects of HMG-CoA reductase inhibitors (statins) besides their lipid-lowering function.

Bettina Haslinger-Löffler1.   

Abstract

The paper by Sharyo et al. shows that statins reduce the severity in a model of renal-ischemia reperfusion injury and raises the therapeutic possibility of using statins as pharmacological intervention against acute kidney injury. This, together with previous studies, indicates that statins exert a wide spectrum of anti-inflammatory, immunomodulatory, and protective effects besides their lipid-lowering function.

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Year:  2008        PMID： 18709024     DOI： 10.1038/ki.2008.323

Source DB:  PubMed          Journal:  Kidney Int        ISSN： 0085-2538            Impact factor:   10.612


  9 in total

Review 1.  Statins and cognitive function: an updated review.

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Journal:  Curr Cardiol Rep       Date:  2015-02       Impact factor: 2.931

2.  Atherosclerosis: Pathogenesis and Key Cellular Processes, Current and Emerging Therapies, Key Challenges, and Future Research Directions.

Authors:  Yee-Hung Chan; Dipak P Ramji
Journal:  Methods Mol Biol       Date:  2022

3.  Key Roles of Inflammation in Atherosclerosis: Mediators Involved in Orchestrating the Inflammatory Response and Its Resolution in the Disease Along with Therapeutic Avenues Targeting Inflammation.

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Journal:  Methods Mol Biol       Date:  2022

Review 4.  Clinical therapeutic strategies for early stage of diabetic kidney disease.

Authors:  Munehiro Kitada; Keizo Kanasaki; Daisuke Koya
Journal:  World J Diabetes       Date:  2014-06-15

Review 5.  Immune mechanisms and novel pharmacological therapies of acute kidney injury.

Authors:  Amandeep Bajwa; Gilbert R Kinsey; Mark D Okusa
Journal:  Curr Drug Targets       Date:  2009-12       Impact factor: 3.465

6.  Acute kidney injury in statin initiators.

Authors:  J Bradley Layton; M Alan Brookhart; Michele Jonsson Funk; Ross J Simpson; Virginia Pate; Til Stürmer; Abhijit V Kshirsagar
Journal:  Pharmacoepidemiol Drug Saf       Date:  2013-08-20       Impact factor: 2.890

7.  Pravastatin stimulates angiogenesis in a murine hindlimb ischemia model: a positron emission tomography imaging study with (64)Cu-NOTA-TRC105.

Authors:  Hakan Orbay; Hao Hong; Jill M Koch; Hector F Valdovinos; Timothy A Hacker; Charles P Theuer; Todd E Barnhart; Weibo Cai
Journal:  Am J Transl Res       Date:  2013-12-01       Impact factor: 4.060

Review 8.  Nutraceutical therapies for atherosclerosis.

Authors:  Joe W E Moss; Dipak P Ramji
Journal:  Nat Rev Cardiol       Date:  2016-07-07       Impact factor: 32.419

9.  Does combined peroxisome proliferator-activated receptors-agonist and pravastatin therapy attenuate the onset of diabetes-induced experimental nephropathy?

Authors:  Hayam I Gad
Journal:  Saudi Med J       Date:  2014-11       Impact factor: 1.484
  9 in total

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