Literature DB >> 18708154

SOCS regulation of the JAK/STAT signalling pathway.

Ben A Croker1, Hiu Kiu, Sandra E Nicholson.   

Abstract

The suppressor of cytokine signalling (SOCS) proteins were, as their name suggests, first described as inhibitors of cytokine signalling. While their actions clearly now extend to other intracellular pathways, they remain key negative regulators of cytokine and growth factor signalling. In this review we focus on the mechanics of SOCS action and the complexities of the mouse models that have underpinned our current understanding of SOCS biology.

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Year:  2008        PMID： 18708154      PMCID： PMC2597703          DOI： 10.1016/j.semcdb.2008.07.010

Source DB:  PubMed          Journal:  Semin Cell Dev Biol        ISSN： 1084-9521            Impact factor:   7.727


  135 in total

1.  A novel ligand for an SH3 domain of the adaptor protein Nck bears an SH2 domain and nuclear signaling motifs.

Authors:  K Matuoka; H Miki; K Takahashi; T Takenawa
Journal:  Biochem Biophys Res Commun       Date:  1997-10-20       Impact factor: 3.575

2.  Structure and function of a new STAT-induced STAT inhibitor.

Authors:  T Naka; M Narazaki; M Hirata; T Matsumoto; S Minamoto; A Aono; N Nishimoto; T Kajita; T Taga; K Yoshizaki; S Akira; T Kishimoto
Journal:  Nature       Date:  1997-06-26       Impact factor: 49.962

3.  A new protein containing an SH2 domain that inhibits JAK kinases.

Authors:  T A Endo; M Masuhara; M Yokouchi; R Suzuki; H Sakamoto; K Mitsui; A Matsumoto; S Tanimura; M Ohtsubo; H Misawa; T Miyazaki; N Leonor; T Taniguchi; T Fujita; Y Kanakura; S Komiya; A Yoshimura
Journal:  Nature       Date:  1997-06-26       Impact factor: 49.962

4.  Twenty proteins containing a C-terminal SOCS box form five structural classes.

Authors:  D J Hilton; R T Richardson; W S Alexander; E M Viney; T A Willson; N S Sprigg; R Starr; S E Nicholson; D Metcalf; N A Nicola
Journal:  Proc Natl Acad Sci U S A       Date:  1998-01-06       Impact factor: 11.205

5.  Interleukin-6 reduces cartilage destruction during experimental arthritis. A study in interleukin-6-deficient mice.

Authors:  F A van de Loo; S Kuiper; F H van Enckevort; O J Arntz; W B van den Berg
Journal:  Am J Pathol       Date:  1997-07       Impact factor: 4.307

6.  Growth hormone preferentially induces the rapid, transient expression of SOCS-3, a novel inhibitor of cytokine receptor signaling.

Authors:  T E Adams; J A Hansen; R Starr; N A Nicola; D J Hilton; N Billestrup
Journal:  J Biol Chem       Date:  1998-01-16       Impact factor: 5.157

7.  Mechanistic and prognostic significance of aberrant methylation in the molecular pathogenesis of human hepatocellular carcinoma.

Authors:  Diego F Calvisi; Sara Ladu; Alexis Gorden; Miriam Farina; Ju-Seog Lee; Elizabeth A Conner; Insa Schroeder; Valentina M Factor; Snorri S Thorgeirsson
Journal:  J Clin Invest       Date:  2007-09       Impact factor: 14.808

8.  Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7.

Authors:  Brandon E Kremer; Laura A Adang; Ian G Macara
Journal:  Cell       Date:  2007-09-07       Impact factor: 41.582

9.  The SOCS box of suppressor of cytokine signaling-3 contributes to the control of G-CSF responsiveness in vivo.

Authors:  Kristy Boyle; Paul Egan; Steven Rakar; Tracy A Willson; Ian P Wicks; Donald Metcalf; Douglas J Hilton; Nicos A Nicola; Warren S Alexander; Andrew W Roberts; Lorraine Robb
Journal:  Blood       Date:  2007-05-17       Impact factor: 22.113

10.  Proteasomes regulate erythropoietin receptor and signal transducer and activator of transcription 5 (STAT5) activation. Possible involvement of the ubiquitinated Cis protein.

Authors:  F Verdier; S Chrétien; O Muller; P Varlet; A Yoshimura; S Gisselbrecht; C Lacombe; P Mayeux
Journal:  J Biol Chem       Date:  1998-10-23       Impact factor: 5.157
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  231 in total

1.  Eltrombopag maintains human hematopoietic stem and progenitor cells under inflammatory conditions mediated by IFN-γ.

Authors:  Luigi J Alvarado; Heather D Huntsman; Hai Cheng; Danielle M Townsley; Thomas Winkler; Xingmin Feng; Cynthia E Dunbar; Neal S Young; Andre Larochelle
Journal:  Blood       Date:  2019-02-25       Impact factor: 22.113

Review 2.  Regulation of the inflammatory response of vascular endothelial cells by EPAC1.

Authors:  Euan Parnell; Brian O Smith; Timothy M Palmer; Anna Terrin; Manuela Zaccolo; Stephen J Yarwood
Journal:  Br J Pharmacol       Date:  2012-05       Impact factor: 8.739

3.  Enforced SOCS1 and SOCS3 expression attenuates Lck-mediated cellular transformation.

Authors:  John C Cooper; Mingjian Shi; Fu-Yu Chueh; Srividya Venkitachalam; Chao-Lan Yu
Journal:  Int J Oncol       Date:  2010-05       Impact factor: 5.650

4.  Galectins regulate the inflammatory response in airway epithelial cells exposed to microbial neuraminidase by modulating the expression of SOCS1 and RIG1.

Authors:  Mihai Nita-Lazar; Aditi Banerjee; Chiguang Feng; Gerardo R Vasta
Journal:  Mol Immunol       Date:  2015-09-06       Impact factor: 4.407

Review 5.  Erythropoietin receptor response circuits.

Authors:  Don M Wojchowski; Pradeep Sathyanarayana; Arvind Dev
Journal:  Curr Opin Hematol       Date:  2010-05       Impact factor: 3.284

6.  Deficiency of Socs3 leads to brain-targeted EAE via enhanced neutrophil activation and ROS production.

Authors:  Zhaoqi Yan; Wei Yang; Luke Parkitny; Sara A Gibson; Kevin S Lee; Forrest Collins; Jessy S Deshane; Wayne Cheng; Amy S Weinmann; Hairong Wei; Hongwei Qin; Etty N Benveniste
Journal:  JCI Insight       Date:  2019-04-02

7.  Signaling by retinol and its serum binding protein.

Authors:  Noa Noy
Journal:  Prostaglandins Leukot Essent Fatty Acids       Date:  2014-10-29       Impact factor: 4.006

8.  miR-29b induces SOCS-1 expression by promoter demethylation and negatively regulates migration of multiple myeloma and endothelial cells.

Authors:  Nicola Amodio; Dina Bellizzi; Marzia Leotta; Lavinia Raimondi; Lavinia Biamonte; Patrizia D'Aquila; Maria Teresa Di Martino; Teresa Calimeri; Marco Rossi; Marta Lionetti; Emanuela Leone; Giuseppe Passarino; Antonino Neri; Antonio Giordano; Pierosandro Tagliaferri; Pierfrancesco Tassone
Journal:  Cell Cycle       Date:  2013-09-25       Impact factor: 4.534

9.  Misregulation of suppressors of cytokine signaling in eosinophilic esophagitis.

Authors:  Ma Paz Zafra; Natally Cancelliere; Pablo Rodríguez del Río; Mónica Ruiz-García; Laura Estévez; Victoria Andregnette; Silvia Sánchez-García; Ana Fiandor; Elena Collantes; Joaquín Sastre; Santiago Quirce; María Dolores Ibáñez; Victoria del Pozo
Journal:  J Gastroenterol       Date:  2012-12-11       Impact factor: 7.527

10.  Socs36E attenuates STAT signaling to optimize motile cell specification in the Drosophila ovary.

Authors:  Amanda J Monahan; Michelle Starz-Gaiano
Journal:  Dev Biol       Date:  2013-04-10       Impact factor: 3.582
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