| Literature DB >> 18708151 |
Abstract
MicroRNAs (miRNAs) are endogenous small regulatory RNAs, which control gene expression in eukaryotes. In plants they repress mRNA targets containing a highly complementary site, either by cleavage or translational repression. Studies of individual miRNA/target interactions highlight the involvement of the miRNA-based regulations in a broad range of developmental programs, throughout plant lifecycle. MicroRNAs can have distinct regulatory functions on their targets: some determine their spatial accumulation, some have a buffering role that ensures the robustness of their expression pattern, and finally others establish the temporal expression of targeted genes.Mesh:
Substances:
Year: 2008 PMID: 18708151 DOI: 10.1016/j.semcdb.2008.07.013
Source DB: PubMed Journal: Semin Cell Dev Biol ISSN: 1084-9521 Impact factor: 7.727