AIMS: Central obesity, a prominent feature of metabolic syndrome (MetS), is commonly assessed by gender- and ethnicity-specific waist circumference (WC) cut-off values. Since 2006, the recommended WC cut-offs by the International Diabetes Federation (IDF) for Europeans are used in Iran because of limited data availability. The purpose of this study was to determine optimal cut-off points for the diagnosis of MetS in Iran. METHODS: A total of 2752 adults (1046 men) were studied. Subjects with two or more of the following risk factors from the IDF criteria were considered to have multiple risk factors: hyperglycemia (FBG>/=100mg/dL or diagnosed diabetes), high blood pressure (SBP>/=130mmHg, DBP>/=85mmHg, or using antihypertensive drugs), low HDL (<50mg/dL for females and <40mg/dL for males), and high TG (>150mg/dL). RESULTS: The WC cut-off yielding maximum sensitivity plus specificity for predicting the presence of multiple risk factors was 91.5cm in men and 85.5cm in women. Sensitivity and specificity were 77% (86%) and 58% (50%) in men (women), respectively. MetS prevalence was estimated to be approximately 27% in Tehran. CONCLUSIONS: WC cut-offs recommended by the IDF are not appropriate for use in Iran.
AIMS: Central obesity, a prominent feature of metabolic syndrome (MetS), is commonly assessed by gender- and ethnicity-specific waist circumference (WC) cut-off values. Since 2006, the recommended WC cut-offs by the International Diabetes Federation (IDF) for Europeans are used in Iran because of limited data availability. The purpose of this study was to determine optimal cut-off points for the diagnosis of MetS in Iran. METHODS: A total of 2752 adults (1046 men) were studied. Subjects with two or more of the following risk factors from the IDF criteria were considered to have multiple risk factors: hyperglycemia (FBG>/=100mg/dL or diagnosed diabetes), high blood pressure (SBP>/=130mmHg, DBP>/=85mmHg, or using antihypertensive drugs), low HDL (<50mg/dL for females and <40mg/dL for males), and high TG (>150mg/dL). RESULTS: The WC cut-off yielding maximum sensitivity plus specificity for predicting the presence of multiple risk factors was 91.5cm in men and 85.5cm in women. Sensitivity and specificity were 77% (86%) and 58% (50%) in men (women), respectively. MetS prevalence was estimated to be approximately 27% in Tehran. CONCLUSIONS: WC cut-offs recommended by the IDF are not appropriate for use in Iran.
Authors: Sh Abbaszadeh Ahranjani; H Kashani; Mh Forouzanfar; Hr Aghaei Meybodi; B Larijani; M Aalaa; Mr Mohajeri-Tehrani Journal: Iran J Public Health Date: 2012-04-30 Impact factor: 1.429
Authors: Ma Kaykhaei; M Hashemi; B Narouie; A Shikhzadeh; M Jahantigh; E Shirzaei; B Rezazehi; M Hoseinian; S Yousefi; S Masoudian; A Emamdadi; Sf Alavi; R Mashhadi; H Ansari Journal: Iran J Public Health Date: 2012-02-29 Impact factor: 1.429