Literature DB >> 18706320

Screening of anti-HIV-1 inophyllums by HPLC-DAD of Calophyllum inophyllum leaf extracts from French Polynesia Islands.

Frédéric Laure1, Phila Raharivelomanana, Jean-François Butaud, Jean-Pierre Bianchini, Emile M Gaydou.   

Abstract

Various pyranocoumarins, calophyllolide, inophyllums B, C, G(1), G(2) and P, from Calophyllum inophyllum (Clusiaceae) leaves of French Polynesia (Austral, Marquesas, Society and Tuamotu archipelagos) have been determined in 136 leaf extracts using a high pressure liquid chromatography-UV-diode array detection (HPLC-UV-DAD) technique. Results show a wide range in chemical composition within trees growing on eighteen islands. The use of multivariate statistical analyses (PCA) shows geographical distribution of inophyllums and indicate those rich in HIV-1 active (+)-inophyllums. Inophyllum B and P contents (0.0-39.0 and 0.0-21.8 mg kg(-1), respectively) confirm the chemodiversity of this species within the large area of French Polynesia. The study suggests the presence of interesting chemotypes which could be used as plant source for anti-HIV-1 drugs.

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Year:  2008        PMID: 18706320     DOI: 10.1016/j.aca.2008.06.046

Source DB:  PubMed          Journal:  Anal Chim Acta        ISSN: 0003-2670            Impact factor:   6.558


  6 in total

1.  The Wound Healing and Antibacterial Activity of Five Ethnomedical Calophyllum inophyllum Oils: An Alternative Therapeutic Strategy to Treat Infected Wounds.

Authors:  Teddy Léguillier; Marylin Lecsö-Bornet; Christelle Lémus; Delphine Rousseau-Ralliard; Nicolas Lebouvier; Edouard Hnawia; Mohammed Nour; William Aalbersberg; Kamelia Ghazi; Phila Raharivelomanana; Patrice Rat
Journal:  PLoS One       Date:  2015-09-25       Impact factor: 3.240

2.  Two new xanthones from Calophyllum nodusum (Guttiferae).

Authors:  Nadiah Mad Nasir; Mawardi Rahmani; Khozirah Shaari; Gwendoline Cheng Lian Ee; Rusea Go; Nur Kartinee Kassim; Siti Noor Kamilah Muhamad; Mohd Johadi Iskandar
Journal:  Molecules       Date:  2011-10-25       Impact factor: 4.411

3.  Chemodiversity of Calophyllum inophyllum L. oil bioactive components related to their specific geographical distribution in the South Pacific region.

Authors:  Joape Ginigini; Gaël J Lecellier; Mael Nicolas; Mohammed Nour; Edouard Hnawia; Nicolas Lebouvier; Gaëtan Herbette; Peter Lockhart; Phila Raharivelomanana
Journal:  PeerJ       Date:  2019-05-22       Impact factor: 2.984

4.  Feature-Based Molecular Networks Identification of Bioactive Metabolites from Three Plants of the Polynesian Cosmetopoeia Targeting the Dermal Papilla Cells of the Hair Cycle.

Authors:  Kristelle Hughes; Raimana Ho; Stéphane Greff; Gaëtan Herbette; Edith Filaire; Edwige Ranouille; Jean-Yves Berthon; Phila Raharivelomanana
Journal:  Molecules       Date:  2021-12-24       Impact factor: 4.411

5.  In silico, in vitro screening of plant extracts for anti-SARS-CoV-2 activity and evaluation of their acute and sub-acute toxicity.

Authors:  Damle Latha; Damle Hrishikesh; Ganju Shiban; C Chandrashekar; B R Bharath
Journal:  Phytomed Plus       Date:  2022-01-31

Review 6.  Medicinal Plants Used in the Treatment of Human Immunodeficiency Virus.

Authors:  Bahare Salehi; Nanjangud V Anil Kumar; Bilge Şener; Mehdi Sharifi-Rad; Mehtap Kılıç; Gail B Mahady; Sanja Vlaisavljevic; Marcello Iriti; Farzad Kobarfard; William N Setzer; Seyed Abdulmajid Ayatollahi; Athar Ata; Javad Sharifi-Rad
Journal:  Int J Mol Sci       Date:  2018-05-14       Impact factor: 5.923

  6 in total

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