Literature DB >> 18705778

A systematic review of silver-releasing dressings in the management of infected chronic wounds.

Shu-Fen Lo1, Mark Hayter, Chee-Jen Chang, Wen-Yu Hu, Ling-Ling Lee.   

Abstract

AIM: This paper is a systematic review with the objective of determining the effectiveness of silver-releasing dressing in the management of infected chronic wounds.
BACKGROUND: Chronic wounds exhibit increased bacterial burdens which not only result in a negative physical impact on patients, impairing their quality of life, but also increase treatment costs. Silver dressings are wound products designed to control and inhibit infection and provide a wound environment conducive to healing. However, there is limited evidence on their effectiveness in doing so.
METHODS: A systematic review of literature from 1950-May 2007 was conducted using the PubMed, CINAHL, Cochrane, MEDLINE, British Nursing Index, EBSCO Host, OCLC, Proquest and PsychInfo databases. The review included randomised or non-randomised control trials, published in English or non-English, of silver-releasing dressings in infected chronic wounds.
RESULTS: Of the over 1957 potentially releasing studies examined, 14 pertinent articles involving 1285 participants were identified. Almost all the participants reported one or more statistically significant outcomes. The main points to emerge from this review of studies are that silver-releasing dressings show positive effects on infected chronic wounds. The quality of the trials was limited by the potential for bias associated with inadequate concealment, no detailed description of the outcome measurement and no reported intention-to-treat analysis. Moreover, problems existed in some studies with confounding factors.
CONCLUSION: The review clearly highlights the need for well-designed, methodologically standardised outcome measurement research into the effectiveness of silver-releasing dressings. It also points to the need for a comprehensive assessment of wound bed status in further studies. RELEVANCE TO CLINICAL PRACTICE: This review strengthens the case for the use of silver dressings when managing infected chronic wounds. They appear more effective and are tolerated well by patients. However, their use should be accompanied by a comprehensive wound assessment.

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Year:  2008        PMID: 18705778     DOI: 10.1111/j.1365-2702.2007.02264.x

Source DB:  PubMed          Journal:  J Clin Nurs        ISSN: 0962-1067            Impact factor:   3.036


  15 in total

1.  Appropriate use of silver dressings in wounds: international consensus document.

Authors:  David Leaper
Journal:  Int Wound J       Date:  2012-10       Impact factor: 3.315

2.  Determination of antibacterial properties and cytocompatibility of silver-loaded coral hydroxyapatite.

Authors:  Yu Zhang; Qing-Shui Yin; Yu Zhang; Hong Xia; Fu-Zhi Ai; Yan-Peng Jiao; Xu-Qiong Chen
Journal:  J Mater Sci Mater Med       Date:  2010-06-05       Impact factor: 3.896

Review 3.  The diagnosis of infection in chronic leg ulcers: A narrative review on clinical practice.

Authors:  Ut T Bui; Kathleen Finlayson; Helen Edwards
Journal:  Int Wound J       Date:  2019-01-29       Impact factor: 3.315

4.  Active Release of Nitric Oxide-Releasing Dendrimers from Electrospun Polyurethane Fibers.

Authors:  Brittany V Worley; Robert J Soto; Paige C Kinsley; Mark H Schoenfisch
Journal:  ACS Biomater Sci Eng       Date:  2016-02-29

Review 5.  Use of silver in the prevention and treatment of infections: silver review.

Authors:  Amani D Politano; Kristin T Campbell; Laura H Rosenberger; Robert G Sawyer
Journal:  Surg Infect (Larchmt)       Date:  2013-02-28       Impact factor: 2.150

6.  Spinal Cord Injury Suppresses Cutaneous Inflammation: Implications for Peripheral Wound Healing.

Authors:  Jessica M Marbourg; Anna Bratasz; Xiaokui Mo; Phillip G Popovich
Journal:  J Neurotrauma       Date:  2016-10-17       Impact factor: 5.269

7.  Osteogenic activity of silver-loaded coral hydroxyapatite and its investigation in vivo.

Authors:  Yu Zhang; Qing-Shui Yin; Chu-Song Zhou; Hong Xia; Ying Zhang; Yan-Peng Jiao
Journal:  J Mater Sci Mater Med       Date:  2014-01-14       Impact factor: 3.896

8.  Chitin membranes containing silver nanoparticles for wound dressing application.

Authors:  Rita Singh; Durgeshwer Singh
Journal:  Int Wound J       Date:  2012-09-07       Impact factor: 3.315

Review 9.  Seeking effective interventions to treat complex wounds: an overview of systematic reviews.

Authors:  Andrea C Tricco; Jesmin Antony; Afshin Vafaei; Paul A Khan; Alana Harrington; Elise Cogo; Charlotte Wilson; Laure Perrier; Wing Hui; Sharon E Straus
Journal:  BMC Med       Date:  2015-04-22       Impact factor: 8.775

10.  The use of biatain Ag in hard-to-heal venous leg ulcers: meta-analysis of randomised controlled trials.

Authors:  David Leaper; Christian Münter; Sylvie Meaume; Alessandro Scalise; Nacho Blanes Mompó; Birte Petersen Jakobsen; Finn Gottrup
Journal:  PLoS One       Date:  2013-07-02       Impact factor: 3.240

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