Literature DB >> 18705627

Chronic anterior uveitis following bacille Calmette-Guérin vaccination: molecular mimicry in action?

Alexander Spratt1, Tim Key, Anthony J Vivian.   

Abstract

A 13-year-old girl developed bilateral chronic anterior uveitis following bacille Calmette-Guérin (BCG) vaccination. HLA testing was negative for B27 but positive for DRB1 *0404, a variant of DR4 often associated with rheumatoid arthritis. The authors propose her HLA repertoire allowed for a BCG-induced abnormal autoimmune response by the mechanism of molecular mimicry.

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Year:  2008        PMID： 18705627     DOI： 10.3928/01913913-20080701-15

Source DB:  PubMed          Journal:  J Pediatr Ophthalmol Strabismus        ISSN： 0191-3913            Impact factor:   1.402


  11 in total

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4.  Proposing low-similarity peptide vaccines against Mycobacterium tuberculosis.

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6.  Clinical Features and Outcomes of Patients With Tubercular Uveitis Treated With Antitubercular Therapy in the Collaborative Ocular Tuberculosis Study (COTS)-1.

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Journal:  JAMA Ophthalmol       Date:  2017-12-01       Impact factor: 7.389

Review 7.  BCG: a vaccine with multiple faces.

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8.  Interferon-gamma release assay as a diagnostic test for tuberculosis-associated uveitis.

Authors:  M Ang; W Wong; C C L Ngan; S-P Chee
Journal:  Eye (Lond)       Date:  2012-02-03       Impact factor: 3.775

Review 9.  Uveitis as a Predictor of Predisposition to Autoimmunity.

Authors:  Jillian A Leibowitz; Arden T Woods; Marc M Kesselman; Bindu S Mayi
Journal:  Cureus       Date:  2020-03-28

10.  Drug-induced uveitis.

Authors:  Nikolas Js London; Sunir J Garg; Ramana S Moorthy; Emmett T Cunningham
Journal:  J Ophthalmic Inflamm Infect       Date:  2013-03-25
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