BACKGROUND: Because of concerns about harmful effects of 100% oxygen on newborn infants, air has started to be used for resuscitation in the delivery room. OBJECTIVE: To describe changes in preductal oxygen saturation (Spo(2)) and heart rate (HR) in the first 10 min after birth in very preterm infants initially resuscitated with 100% oxygen (OX(100)) or air (OX(21)). PATIENTS AND METHODS: In July 2006, policy changed from using 100% oxygen to air. Observations of Spo(2) and HR before and after the change were recorded whenever a member of the research team was available to attend the birth. RESULTS: There were 20 infants in the OX(100) group and 106 in the OX(21) group. In the OX(100) group, Spo(2) had risen to a median of 84% after 2 min and 94% by 5 min. In the OX(21) group, median Spo(2) was 31% at 2 min and 54% at 5 min. In the OX(21) group, 92% received supplemental oxygen at a median of 5 min; the Spo(2) rose to a median of 81% by 6 min. In the first 10 min after birth, 80% and 55% of infants in the OX(100) and OX(21) groups, respectively, had an Spo(2) > or =95%. Increases in HR over the first 10 min were very similar in the two groups. CONCLUSIONS: Most very preterm infants received supplemental oxygen if air was used for the initial resuscitation. In these infants, the use of backup 100% oxygen and titration against Spo(2) resulted in a similar course to "normal" term and preterm infants. Of the infants resuscitated with 100% oxygen, 80% had Spo(2) > or =95% during the first 10 min. The HR changes in the two groups were very similar.
BACKGROUND: Because of concerns about harmful effects of 100% oxygen on newborn infants, air has started to be used for resuscitation in the delivery room. OBJECTIVE: To describe changes in preductal oxygen saturation (Spo(2)) and heart rate (HR) in the first 10 min after birth in very preterm infants initially resuscitated with 100% oxygen (OX(100)) or air (OX(21)). PATIENTS AND METHODS: In July 2006, policy changed from using 100% oxygen to air. Observations of Spo(2) and HR before and after the change were recorded whenever a member of the research team was available to attend the birth. RESULTS: There were 20 infants in the OX(100) group and 106 in the OX(21) group. In the OX(100) group, Spo(2) had risen to a median of 84% after 2 min and 94% by 5 min. In the OX(21) group, median Spo(2) was 31% at 2 min and 54% at 5 min. In the OX(21) group, 92% received supplemental oxygen at a median of 5 min; the Spo(2) rose to a median of 81% by 6 min. In the first 10 min after birth, 80% and 55% of infants in the OX(100) and OX(21) groups, respectively, had an Spo(2) > or =95%. Increases in HR over the first 10 min were very similar in the two groups. CONCLUSIONS: Most very preterm infants received supplemental oxygen if air was used for the initial resuscitation. In these infants, the use of backup 100% oxygen and titration against Spo(2) resulted in a similar course to "normal" term and preterm infants. Of the infants resuscitated with 100% oxygen, 80% had Spo(2) > or =95% during the first 10 min. The HR changes in the two groups were very similar.
Authors: Vishal S Kapadia; Lina F Chalak; John E Sparks; James R Allen; Rashmin C Savani; Myra H Wyckoff Journal: Pediatrics Date: 2013-11-11 Impact factor: 7.124
Authors: Munmun Rawat; Praveen K Chandrasekharan; Daniel D Swartz; Bobby Mathew; Jayasree Nair; Sylvia F Gugino; Carmon Koenigsknecht; Payam Vali; Satyan Lakshminrusimha Journal: Pediatr Res Date: 2015-12-16 Impact factor: 3.756
Authors: Anne C C Lee; Simon Cousens; Stephen N Wall; Susan Niermeyer; Gary L Darmstadt; Waldemar A Carlo; William J Keenan; Zulfiqar A Bhutta; Christopher Gill; Joy E Lawn Journal: BMC Public Health Date: 2011-04-13 Impact factor: 3.295
Authors: Kei Lui; Lisa J Jones; Jann P Foster; Peter G Davis; See Kwee Ching; Ju Lee Oei; David A Osborn Journal: Cochrane Database Syst Rev Date: 2018-05-04