Literature DB >> 18703256

Synthesis of novel N-protected hydrophobic phenylalanines and their application in potential antibacterials.

Timothy P Boyle1, John B Bremner, Jonathan A Coates, John Deadman, Paul A Keller, Stephen G Pyne, Kittiya Somphol.   

Abstract

An efficient synthesis of two new N-acetyl-4'-arylphenylalanines is described together with their incorporation into a number of cationic peptoid antibacterial agents, one of which had an MIC of 7.8 microg/mL against Staphylococcus aureus.

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Year:  2008        PMID: 18703256     DOI: 10.1016/j.ejmech.2008.07.001

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN: 0223-5234            Impact factor:   6.514


  2 in total

1.  Synthesis and Explosion Hazards of 4-Azido-l-phenylalanine.

Authors:  Mark B Richardson; Derek B Brown; Carlos A Vasquez; Joseph W Ziller; Kevin M Johnston; Gregory A Weiss
Journal:  J Org Chem       Date:  2018-04-02       Impact factor: 4.354

2.  Effect of alkyl chain length on sphingosine kinase 2 selectivity.

Authors:  Kenneth Knott; Yugesh Kharel; Mithun R Raje; Kevin R Lynch; Webster L Santos
Journal:  Bioorg Med Chem Lett       Date:  2012-01-26       Impact factor: 2.823

  2 in total

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