| Literature DB >> 18698819 |
María J Ortega1, Eva Zubía, M Carmen Sánchez, J Luis Carballo.
Abstract
The new cembrane diterpenes leptodienone A (2) and leptodienone B (3) and the known compounds lopholide, lophodiol B, lophodione, and lophotoxin (1) have been isolated from the gorgonian Leptogorgia laxa collected in the Gulf of California. The structures of the new metabolites have been established by spectroscopic techniques. The in vitro cytotoxicity of the new compounds has been tested against three human tumor cell lines.Entities:
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Year: 2008 PMID： 18698819 DOI： 10.1021/np8002639
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050