| Literature DB >> 18698647 |
Pinaki S Bhadury1, Yuping Zhang, Sha Zhang, Baoan Song, Song Yang, Deyu Hu, Zhuo Chen, Wei Xue, Linhong Jin.
Abstract
Asymmetric addition of dialkyl phosphites (--CH2CH3, --CH2CH2CH3, --CH(CH3)2, --CH2(CH2)3CH3, --CH2CH2OCH3 and --CH2CH2OC2H5) induced by chiral organocatalyst e.g. (R)- and (S)-3,3'-[3,5-bis(trifluoromethyl)phenyl]2-1,1'-binaphthyl phosphate on fluorinated aldimines derived from cinnamaldehyde has been found effective to give new bioactive alpha-aminophosphonates in good yields (58-73%) and high enantiomeric excess (64.6%-90.6%) under mild conditions.Entities:
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Year: 2009 PMID： 18698647 DOI： 10.1002/chir.20645
Source DB: PubMed Journal: Chirality ISSN： 0899-0042 Impact factor: 2.437