OBJECTIVE: To describe the prevalence and causes of low vision and blindness in a Malay population. METHODS: A population-based, cross-sectional study of 3280 participants of Malay ethnicity, aged 40 to 79 years, was conducted. Participants underwent standardized ophthalmic assessments to determine (1) presenting and best-corrected visual acuity according to US and modified World Health Organization definitions of blindness and low vision and (2) the primary causes of visual impairment. RESULTS: Of 4168 eligible individuals, 3280 participated in the study (78.7%). The population-weighted prevalence of bilateral blindness was 0.3% and of bilateral low vision, 4.4% (US definition of presenting visual acuity). After best-corrected visual acuity, the population-weighted prevalence of bilateral blindness was reduced to 0.1% and bilateral low vision to 1.0%. Cataract was the main cause of presenting unilateral (38.9%) and bilateral (65.2%) blindness, whereas undercorrected refractive error was the main cause of presenting unilateral (68.8%) and bilateral (52.2%) low vision. Diabetic retinopathy, age-related macular degeneration, and glaucoma were the other leading causes of blindness and low vision. CONCLUSIONS: The age-standardized prevalences of bilateral blindness and low vision in a Malay population were lower when compared with other Asian studies. Undercorrected refractive error and cataract are the leading causes of visual impairment among the Malay adult population in Singapore.
OBJECTIVE: To describe the prevalence and causes of low vision and blindness in a Malay population. METHODS: A population-based, cross-sectional study of 3280 participants of Malay ethnicity, aged 40 to 79 years, was conducted. Participants underwent standardized ophthalmic assessments to determine (1) presenting and best-corrected visual acuity according to US and modified World Health Organization definitions of blindness and low vision and (2) the primary causes of visual impairment. RESULTS: Of 4168 eligible individuals, 3280 participated in the study (78.7%). The population-weighted prevalence of bilateral blindness was 0.3% and of bilateral low vision, 4.4% (US definition of presenting visual acuity). After best-corrected visual acuity, the population-weighted prevalence of bilateral blindness was reduced to 0.1% and bilateral low vision to 1.0%. Cataract was the main cause of presenting unilateral (38.9%) and bilateral (65.2%) blindness, whereas undercorrected refractive error was the main cause of presenting unilateral (68.8%) and bilateral (52.2%) low vision. Diabetic retinopathy, age-related macular degeneration, and glaucoma were the other leading causes of blindness and low vision. CONCLUSIONS: The age-standardized prevalences of bilateral blindness and low vision in a Malay population were lower when compared with other Asian studies. Undercorrected refractive error and cataract are the leading causes of visual impairment among the Malay adult population in Singapore.
Authors: Christian Wolfram; Alexander K Schuster; Heike M Elflein; Stefan Nickels; Andreas Schulz; Philipp S Wild; Manfred E Beutel; Maria Blettner; Thomas Münzel; Karl J Lackner; Norbert Pfeiffer Journal: Dtsch Arztebl Int Date: 2019-04-26 Impact factor: 5.594
Authors: Ruchir Srivastava; Xinting Gao; Fengshou Yin; Damon W K Wong; Jiang Liu; Carol Y Cheung; Tien Yin Wong Journal: J Med Imaging (Bellingham) Date: 2014-06-04
Authors: Ching-Yu Cheng; Maria Schache; M Kamran Ikram; Terri L Young; Jeremy A Guggenheim; Veronique Vitart; Stuart MacGregor; Virginie J M Verhoeven; Veluchamy A Barathi; Jiemin Liao; Pirro G Hysi; Joan E Bailey-Wilson; Beate St Pourcain; John P Kemp; George McMahon; Nicholas J Timpson; David M Evans; Grant W Montgomery; Aniket Mishra; Ya Xing Wang; Jie Jin Wang; Elena Rochtchina; Ozren Polasek; Alan F Wright; Najaf Amin; Elisabeth M van Leeuwen; James F Wilson; Craig E Pennell; Cornelia M van Duijn; Paulus T V M de Jong; Johannes R Vingerling; Xin Zhou; Peng Chen; Ruoying Li; Wan-Ting Tay; Yingfeng Zheng; Merwyn Chew; Kathryn P Burdon; Jamie E Craig; Sudha K Iyengar; Robert P Igo; Jonathan H Lass; Emily Y Chew; Toomas Haller; Evelin Mihailov; Andres Metspalu; Juho Wedenoja; Claire L Simpson; Robert Wojciechowski; René Höhn; Alireza Mirshahi; Tanja Zeller; Norbert Pfeiffer; Karl J Lackner; Thomas Bettecken; Thomas Meitinger; Konrad Oexle; Mario Pirastu; Laura Portas; Abhishek Nag; Katie M Williams; Ekaterina Yonova-Doing; Ronald Klein; Barbara E Klein; S Mohsen Hosseini; Andrew D Paterson; Kari-Matti Makela; Terho Lehtimaki; Mika Kahonen; Olli Raitakari; Nagahisa Yoshimura; Fumihiko Matsuda; Li Jia Chen; Chi Pui Pang; Shea Ping Yip; Maurice K H Yap; Akira Meguro; Nobuhisa Mizuki; Hidetoshi Inoko; Paul J Foster; Jing Hua Zhao; Eranga Vithana; E-Shyong Tai; Qiao Fan; Liang Xu; Harry Campbell; Brian Fleck; Igor Rudan; Tin Aung; Albert Hofman; André G Uitterlinden; Goran Bencic; Chiea-Chuen Khor; Hannah Forward; Olavi Pärssinen; Paul Mitchell; Fernando Rivadeneira; Alex W Hewitt; Cathy Williams; Ben A Oostra; Yik-Ying Teo; Christopher J Hammond; Dwight Stambolian; David A Mackey; Caroline C W Klaver; Tien-Yin Wong; Seang-Mei Saw; Paul N Baird Journal: Am J Hum Genet Date: 2013-08-08 Impact factor: 11.025