| Literature DB >> 18694727 |
Marleen Van Troys1, Anja Lambrechts, Violaine David, Hans Demol, Magda Puype, Javier Pizarro-Cerda, Kris Gevaert, Pascale Cossart, Joël Vandekerckhove.
Abstract
Actin-based comet tails produced by Listeria monocytogenes are considered as representative models for cellular force-producing machineries crucial for cell migration. We here present a proteomic picture of these tails formed in extracts from brain and platelets. This provides a comprehensive view, revealing high molecular complexity and novel host cell proteins as tail components, and suggests the participation of specific multicomponent regulatory complexes. This work forms a new basis to expand current models of cellular protrusion.Entities:
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Year: 2008 PMID： 18694727 DOI： 10.1016/j.bbrc.2008.07.152
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575