| Literature DB >> 18694641 |
David A Scott1, Brian M Aquila, Geraldine A Bebernitz, Donald J Cook, Les A Dakin, Tracy L Deegan, Maureen M Hattersley, Stephanos Ioannidis, Paul D Lyne, Charles A Omer, Minwei Ye, Xiaolan Zheng.
Abstract
The bisamide class of kinase inhibitors was identified as being active against CSF-1R. The synthesis and SAR of pyridyl and thiazolyl bisamides are reported, along with the pharmacokinetic properties and in vivo activity of selected examples.Entities:
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Year: 2008 PMID: 18694641 DOI: 10.1016/j.bmcl.2008.07.093
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN: 0960-894X Impact factor: 2.823