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Literature DB >> 18694557

A descent into the nuage: the maelstrom of transposon control.

Kathryn A O'Donnell¹, Kathleen H Burns, Jef D Boeke.

Abstract

In this issue of Developmental Cell, Soper et al. (2008) report that the mammalian MAELSTROM (MAEL) protein is critical for transposon silencing in the male germline. Loss of MAEL is associated with meiotic failure and DNA damage, suggesting that efficient transposable element restraining mechanisms must be in place for the preservation of germline integrity.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 2008 PMID： 18694557 PMCID： PMC2867346 DOI： 10.1016/j.devcel.2008.07.016

Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270

10 in total

Review 1. Sex matters in meiosis.

Authors: Patricia A Hunt; Terry J Hassold
Journal: Science Date: 2002-06-21 Impact factor: 47.728

Review 2. Biogenesis and germline functions of piRNAs.

Authors: Carla Klattenhoff; William Theurkauf
Journal: Development Date: 2007-11-21 Impact factor: 6.868

Review 3. The Piwi-piRNA pathway provides an adaptive defense in the transposon arms race.

Authors: Alexei A Aravin; Gregory J Hannon; Julius Brennecke
Journal: Science Date: 2007-11-02 Impact factor: 47.728

4. maelstrom is required for an early step in the establishment of Drosophila oocyte polarity: posterior localization of grk mRNA.

Authors: N J Clegg; D M Frost; M K Larkin; L Subrahmanyan; Z Bryant; H Ruohola-Baker
Journal: Development Date: 1997-11 Impact factor: 6.868

5. Maelstrom, a Drosophila spindle-class gene, encodes a protein that colocalizes with Vasa and RDE1/AGO1 homolog, Aubergine, in nuage.

Authors: Seth D Findley; Mio Tamanaha; Nigel J Clegg; Hannele Ruohola-Baker
Journal: Development Date: 2003-03 Impact factor: 6.868

6. DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes.

Authors: Satomi Kuramochi-Miyagawa; Toshiaki Watanabe; Kengo Gotoh; Yasushi Totoki; Atsushi Toyoda; Masahito Ikawa; Noriko Asada; Kanako Kojima; Yuka Yamaguchi; Takashi W Ijiri; Kenichiro Hata; En Li; Yoichi Matsuda; Tohru Kimura; Masaru Okabe; Yoshiyuki Sakaki; Hiroyuki Sasaki; Toru Nakano
Journal: Genes Dev Date: 2008-04-01 Impact factor: 11.361

7. Mouse maelstrom, a component of nuage, is essential for spermatogenesis and transposon repression in meiosis.

Authors: Sarah F C Soper; Godfried W van der Heijden; Tara C Hardiman; Mary Goodheart; Sandra L Martin; Peter de Boer; Alex Bortvin
Journal: Dev Cell Date: 2008-08 Impact factor: 12.270

8. The human LINE-1 retrotransposon creates DNA double-strand breaks.

Authors: Stephen L Gasior; Timothy P Wakeman; Bo Xu; Prescott L Deininger
Journal: J Mol Biol Date: 2006-02-09 Impact factor: 5.469

9. Unique germ-line organelle, nuage, functions to repress selfish genetic elements in Drosophila melanogaster.

Authors: Ai Khim Lim; Toshie Kai
Journal: Proc Natl Acad Sci U S A Date: 2007-04-11 Impact factor: 11.205

10. Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?

Authors: Yael Costa; Robert M Speed; Philippe Gautier; Colin A Semple; Klio Maratou; James M A Turner; Howard J Cooke
Journal: Hum Mol Genet Date: 2006-06-20 Impact factor: 6.150

10 in total

Review 1. Male germline control of transposable elements.

Authors: Jianqiang Bao; Wei Yan
Journal: Biol Reprod Date: 2012-05-31 Impact factor: 4.285

Review 2. Roles for the lipid-signaling enzyme MitoPLD in mitochondrial dynamics, piRNA biogenesis, and spermatogenesis.

Authors: Qun Gao; Michael A Frohman
Journal: BMB Rep Date: 2012-01 Impact factor: 4.778

Review 3. Nuage proteins: their localization in subcellular structures of spermatogenic cells as revealed by immunoelectron microscopy.

Authors: Sadaki Yokota
Journal: Histochem Cell Biol Date: 2012-05-15 Impact factor: 4.304

A descent into the nuage: the maelstrom of transposon control.

Review 1. Sex matters in meiosis.

Review 2. Biogenesis and germline functions of piRNAs.

Review 3. The Piwi-piRNA pathway provides an adaptive defense in the transposon arms race.

4. maelstrom is required for an early step in the establishment of Drosophila oocyte polarity: posterior localization of grk mRNA.

5. Maelstrom, a Drosophila spindle-class gene, encodes a protein that colocalizes with Vasa and RDE1/AGO1 homolog, Aubergine, in nuage.

6. DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes.

7. Mouse maelstrom, a component of nuage, is essential for spermatogenesis and transposon repression in meiosis.

8. The human LINE-1 retrotransposon creates DNA double-strand breaks.

9. Unique germ-line organelle, nuage, functions to repress selfish genetic elements in Drosophila melanogaster.

10. Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?

Review 1. Male germline control of transposable elements.

Review 2. Roles for the lipid-signaling enzyme MitoPLD in mitochondrial dynamics, piRNA biogenesis, and spermatogenesis.

Review 3. Nuage proteins: their localization in subcellular structures of spermatogenic cells as revealed by immunoelectron microscopy.

Review 4. The Human Long Interspersed Element-1 Retrotransposon: An Emerging Biomarker of Neoplasia.

Review 5. Mammalian phospholipase D physiological and pathological roles.

6. DNA transposon Hermes inserts into DNA in nucleosome-free regions in vivo.

Review 7. Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling.

8. A role for retrotransposon LINE-1 in fetal oocyte attrition in mice.

9. Biomarker potential of repetitive-element transcriptome in lung cancer.

10. TE-array--a high throughput tool to study transposon transcription.