Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 BMP signaling goes posttranscriptional in a microRNA sort of way.

Literature DB >> 18694554

BMP signaling goes posttranscriptional in a microRNA sort of way.

Abstract

Aberrant microRNA (miRNA) expression correlates with human diseases such as cardiac disorders and cancer. Treatment of such disorders using miRNA-targeted therapeutics requires a thorough understanding of miRNA regulation in vivo. A recent paper in Nature by Davis et al. expands our understanding of miRNA biogenesis and maturation, elucidating a mechanism by which extracellular signaling directs cell differentiation via posttranscriptional regulation of miRNA expression.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 2008 PMID： 18694554 PMCID： PMC2921160 DOI： 10.1016/j.devcel.2008.07.015

Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270

9 in total

Review 1. miRNAs on the move: miRNA biogenesis and the RNAi machinery.

Authors: Elizabeth P Murchison; Gregory J Hannon
Journal: Curr Opin Cell Biol Date: 2004-06 Impact factor: 8.382

2. Post-transcriptional regulation of microRNA expression.

Authors: Gregor Obernosterer; Philipp J F Leuschner; Mattias Alenius; Javier Martinez
Journal: RNA Date: 2006-05-31 Impact factor: 4.942

3. Extensive post-transcriptional regulation of microRNAs and its implications for cancer.

Authors: J Michael Thomson; Martin Newman; Joel S Parker; Elizabeth M Morin-Kensicki; Tricia Wright; Scott M Hammond
Journal: Genes Dev Date: 2006-08-01 Impact factor: 11.361

4. DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs.

Authors: Toru Fukuda; Kaoru Yamagata; Sally Fujiyama; Takahiro Matsumoto; Iori Koshida; Kimihiro Yoshimura; Masatomo Mihara; Masanori Naitou; Hideki Endoh; Takashi Nakamura; Chihiro Akimoto; Yoko Yamamoto; Takenobu Katagiri; Charles Foulds; Shinichiro Takezawa; Hirochika Kitagawa; Ken-ichi Takeyama; Bert W O'Malley; Shigeaki Kato
Journal: Nat Cell Biol Date: 2007-04-15 Impact factor: 28.824

5. MicroRNA expression signature and antisense-mediated depletion reveal an essential role of MicroRNA in vascular neointimal lesion formation.

Authors: Ruirui Ji; Yunhui Cheng; Junming Yue; Jian Yang; Xiaojun Liu; He Chen; David B Dean; Chunxiang Zhang
Journal: Circ Res Date: 2007-05-03 Impact factor: 17.367

6. Systematic evaluation of microRNA processing patterns in tissues, cell lines, and tumors.

Authors: Eun Joo Lee; Myungwon Baek; Yuriy Gusev; Daniel J Brackett; Gerard J Nuovo; Thomas D Schmittgen
Journal: RNA Date: 2007-11-19 Impact factor: 4.942

7. Functional interaction between Smad, CREB binding protein, and p68 RNA helicase.

Authors: Dennis R Warner; Vasker Bhattacherjee; Xiaolong Yin; Saurabh Singh; Partha Mukhopadhyay; M Michele Pisano; Robert M Greene
Journal: Biochem Biophys Res Commun Date: 2004-11-05 Impact factor: 3.575

8. SMAD proteins control DROSHA-mediated microRNA maturation.

Authors: Brandi N Davis; Aaron C Hilyard; Giorgio Lagna; Akiko Hata
Journal: Nature Date: 2008-06-11 Impact factor: 49.962

9. Control of phenotypic plasticity of smooth muscle cells by bone morphogenetic protein signaling through the myocardin-related transcription factors.

Authors: Giorgio Lagna; Manching M Ku; Peter H Nguyen; Nicole A Neuman; Brandi N Davis; Akiko Hata
Journal: J Biol Chem Date: 2007-10-17 Impact factor: 5.157