Literature DB >> 18693954

A model browser for biosimulation.

G Yngve1, J F Brinkley, D Cook, L G Shapiro.   

Abstract

The complexities of biological simulation present difficulties with modeling and experimenting. Simulators process models represented as code, whereas biologists think about abstract models. Our ModelBrowser addresses this difficulty through interactive visualization. Variables and equations appear as a directed graph of nodes and edges, and the user can search and browse this graph by performing queries on metadata associated with the variables and the connectivity of the edges. The browser also supports a hierarchical categorization of the variables, such as by an ontology. We believe that the ModelBrowser will help biologists reason about code in the context of the abstract model, so that they can understand and modify others' code and debug their own.

Mesh:

Year:  2007        PMID: 18693954      PMCID: PMC2655884     

Source DB:  PubMed          Journal:  AMIA Annu Symp Proc        ISSN: 1559-4076


  7 in total

1.  A reference ontology for biomedical informatics: the Foundational Model of Anatomy.

Authors:  Cornelius Rosse; José L V Mejino
Journal:  J Biomed Inform       Date:  2003-12       Impact factor: 6.317

Review 2.  CellML: its future, present and past.

Authors:  Catherine M Lloyd; Matt D B Halstead; Poul F Nielsen
Journal:  Prog Biophys Mol Biol       Date:  2004 Jun-Jul       Impact factor: 3.667

3.  Evolution of a Foundational Model of Physiology: symbolic representation for functional bioinformatics.

Authors:  Daniel L Cook; Jose L V Mejino; Cornelius Rosse
Journal:  Stud Health Technol Inform       Date:  2004

4.  Top scientific visualization research problems.

Authors:  Chris Johnson
Journal:  IEEE Comput Graph Appl       Date:  2004 Jul-Aug       Impact factor: 2.088

5.  Ontology-based representation of simulation models of physiology.

Authors:  Daniel L Rubin; David Grossman; Maxwell Neal; Daniel L Cook; James B Bassingthwaighte; Mark A Musen
Journal:  AMIA Annu Symp Proc       Date:  2006

6.  Hierarchical edge bundles: visualization of adjacency relations in hierarchical data.

Authors:  Danny Holten
Journal:  IEEE Trans Vis Comput Graph       Date:  2006 Sep-Oct       Impact factor: 4.579

7.  Chalkboard: ontology-based pathway modeling and qualitative inference of disease mechanisms.

Authors:  Daniel L Cook; Jesse C Wiley; John H Gennari
Journal:  Pac Symp Biocomput       Date:  2007
  7 in total
  1 in total

1.  JSim, an open-source modeling system for data analysis.

Authors:  Erik Butterworth; Bartholomew E Jardine; Gary M Raymond; Maxwell L Neal; James B Bassingthwaighte
Journal:  F1000Res       Date:  2013-12-30
  1 in total

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