Combined radiofrequency ablation and antiangiogenic drug for the treatment of recurrent renal tumor.

The efficacy of radiofrequency ablation of large renal tumors can be increased by modulating their size and vascularity with antiangiogenic drugs, which may limit the sink effect related to high blood flow. We present an observation with 3 recurrent tumor locations, the largest being 3.7 cm in diameter. Pretreatment with antiangiogenics provided a significant reduction of tumor size and perfusion, allowing efficient ablation under favorable conditions.