Literature DB >> 18692321

Music facilitate the neurogenesis, regeneration and repair of neurons.

Hajime Fukui1, Kumiko Toyoshima.   

Abstract

Experience has shown that therapy using music for therapeutic purposes has certain effects on neuropsychiatric disorders (both functional and organic disorders). However, the mechanisms of action underlying music therapy remain unknown, and scientific clarification has not advanced. While that study disproved the Mozart effect, the effects of music on the human body and mind were not disproved. In fact, more scientific studies on music have been conducted in recent years, mainly in the field of neuroscience, and the level of interest among researchers is increasing. The results of past studies have clarified that music influences and affects cranial nerves in humans from fetus to adult. The effects of music at a cellular level have not been clarified, and the mechanisms of action for the effects of music on the brain have not been elucidated. We propose that listening to music facilitates the neurogenesis, the regeneration and repair of cerebral nerves by adjusting the secretion of steroid hormones, ultimately leading to cerebral plasticity. Music affects levels of such steroids as cortisol (C), testosterone (T) and estrogen (E), and we believe that music also affects the receptor genes related to these substances, and related proteins. In the prevention of Alzheimer's disease and dementia, hormone replacement therapy has been shown to be effective, but at the same time, side effects have been documented, and the clinical application of hormone replacement therapy is facing a serious challenge. Conversely, music is noninvasive, and its existence is universal and mundane. Thus, if music can be used in medical care, the application of such a safe and inexpensive therapeutic option is limitless.

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Year:  2008        PMID: 18692321     DOI: 10.1016/j.mehy.2008.06.019

Source DB:  PubMed          Journal:  Med Hypotheses        ISSN: 0306-9877            Impact factor:   1.538


  20 in total

1.  Changes caused by haloperidol are blocked by music in Wistar rat.

Authors:  Inmaculada Tasset; Ismael Quero; Ángel D García-Mayórgaz; Manuel Causse del Río; Isaac Túnez; Pedro Montilla
Journal:  J Physiol Biochem       Date:  2012-02-28       Impact factor: 4.158

2.  Common carp (Cyprinus carpio) response to two pieces of music ("Eine Kleine Nachtmusik" and "Romanza") combined with light intensity, using recirculating water system.

Authors:  Sofronios E Papoutsoglou; Nafsika Karakatsouli; Eustratios S Papoutsoglou; Georgios Vasilikos
Journal:  Fish Physiol Biochem       Date:  2009-04-30       Impact factor: 2.794

Review 3.  Role of sound stimulation in reprogramming brain connectivity.

Authors:  Sraboni Chaudhury; Tapas C Nag; Suman Jain; Shashi Wadhwa
Journal:  J Biosci       Date:  2013-09       Impact factor: 1.826

4.  Efficacy of music therapy in treatment for the patients with Alzheimer's disease.

Authors:  H Fukui; A Arai; K Toyoshima
Journal:  Int J Alzheimers Dis       Date:  2012-09-26

5.  Maternal Music Exposure during Pregnancy Influences Neonatal Behaviour: An Open-Label Randomized Controlled Trial.

Authors:  Ravindra Arya; Maya Chansoria; Ramesh Konanki; Dileep K Tiwari
Journal:  Int J Pediatr       Date:  2012-02-14

Review 6.  Musical training as an alternative and effective method for neuro-education and neuro-rehabilitation.

Authors:  Clément François; Jennifer Grau-Sánchez; Esther Duarte; Antoni Rodriguez-Fornells
Journal:  Front Psychol       Date:  2015-04-28

7.  Musical neurofeedback for treating depression in elderly people.

Authors:  Rafael Ramirez; Manel Palencia-Lefler; Sergio Giraldo; Zacharias Vamvakousis
Journal:  Front Neurosci       Date:  2015-10-02       Impact factor: 4.677

Review 8.  Music-based cognitive remediation therapy for patients with traumatic brain injury.

Authors:  Shantala Hegde
Journal:  Front Neurol       Date:  2014-03-24       Impact factor: 4.003

Review 9.  Neural implementation of musical expertise and cognitive transfers: could they be promising in the framework of normal cognitive aging?

Authors:  Baptiste Fauvel; Mathilde Groussard; Francis Eustache; Béatrice Desgranges; Hervé Platel
Journal:  Front Hum Neurosci       Date:  2013-10-22       Impact factor: 3.169

10.  Influence of music on steroid hormones and the relationship between receptor polymorphisms and musical ability: a pilot study.

Authors:  Hajime Fukui; Kumiko Toyoshima
Journal:  Front Psychol       Date:  2013-12-03
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