Literature DB >> 18691761

East meets West: how China almost cured malaria.

William R Burns1.   

Abstract

With the isolation of quinine from Cinchona in 1820, an ancient herbal cure was transformed into a chemical drug. This was the inspiration for a new scientific discipline - ethnopharmacology - as Western scientists began to reinvent traditional herbal cures by extracting their active principles to make new and profitable drugs. The Chinese government may claim many such success stories as their own, but such triumphant narratives only reveal part of the story. The drawn-out hunt for the active principle of another anti-malarial herb, changshan, or Dichroa febrifuga, offers a more nuanced narrative that captures the complex interplay between traditional Chinese and Western medicine.

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Year:  2008        PMID: 18691761     DOI: 10.1016/j.endeavour.2008.07.001

Source DB:  PubMed          Journal:  Endeavour        ISSN: 0160-9327            Impact factor:   0.444


  7 in total

1.  From branch to bedside: Youyou Tu is awarded the 2011 Lasker~DeBakey Clinical Medical Research Award for discovering artemisinin as a treatment for malaria.

Authors:  Ushma S Neill
Journal:  J Clin Invest       Date:  2011-10       Impact factor: 14.808

2.  The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs.

Authors:  Jonathan D Herman; Lauren R Pepper; Joseph F Cortese; Guillermina Estiu; Kevin Galinsky; Vanessa Zuzarte-Luis; Emily R Derbyshire; Ulf Ribacke; Amanda K Lukens; Sofia A Santos; Vishal Patel; Clary B Clish; William J Sullivan; Huihao Zhou; Selina E Bopp; Paul Schimmel; Susan Lindquist; Jon Clardy; Maria M Mota; Tracy L Keller; Malcolm Whitman; Olaf Wiest; Dyann F Wirth; Ralph Mazitschek
Journal:  Sci Transl Med       Date:  2015-05-20       Impact factor: 17.956

3.  Combining traditional medicine and modern chemistry to fight malaria.

Authors:  Christiaan van Ooij
Journal:  Ann Transl Med       Date:  2016-12

4.  The Adaptive Proline Response in P. falciparum Is Independent of PfeIK1 and eIF2α Signaling.

Authors:  Lola Fagbami; Amy A Deik; Kritika Singh; Sofia A Santos; Jonathan D Herman; Selina E Bopp; Amanda K Lukens; Clary B Clish; Dyann F Wirth; Ralph Mazitschek
Journal:  ACS Infect Dis       Date:  2019-02-21       Impact factor: 5.084

Review 5.  Nanomedicines for Malaria Chemotherapy: Encapsulation vs. Polymer Therapeutics.

Authors:  Sindisiwe Mvango; William M R Matshe; Abideen O Balogun; Lynne A Pilcher; Mohammed O Balogun
Journal:  Pharm Res       Date:  2018-10-15       Impact factor: 4.200

6.  From bark to weed: the history of artemisinin.

Authors:  C Faurant
Journal:  Parasite       Date:  2011-08       Impact factor: 3.000

7.  Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance.

Authors:  N Connor Payne; Catrine Johansson; Mark A Tye; Kritika Singh; Sofia A Santos; Lọla Fagbami; Akansha Pant; Kayla Sylvester; Madeline R Luth; Sofia Marques; Malcolm Whitman; Maria M Mota; Elizabeth A Winzeler; Amanda K Lukens; Emily R Derbyshire; Udo Oppermann; Dyann F Wirth; Ralph Mazitschek
Journal:  Nat Commun       Date:  2022-08-25       Impact factor: 17.694

  7 in total

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