PURPOSE: To evaluate the occurrence and distribution of mild traumatic brain injury (MTBI) caused by diffuse axonal injury (DAI) using magnetic resonance (MR) imaging and to attempt to correlate MR findings with post-concussion symptoms (PCS). PATIENTS AND METHODS: Forty MTBI patients (mean age: 32.5 years) with normal cranial computed tomography (CT) findings were examined with standard MR protocol including T(1)-weighted, T(2)-weighted, fluid attenuated inversion recovery (FLAIR), gradient echo (GRE) and diffusion-weighted (DW) sequences. MR imaging was performed within 24 hours of injury. The lesions were classified as DAI based on their location and morphologic appearance. RESULTS: In MR imaging of five (12.5%) of the patients, the lesions compatible with DAI were observed. Four patients (10%) had the foci of low signal intensity compatible with hemorrhagic shear injury on the GRE sequence, and five (12.5%) patients had high signal intensity on FLAIR and DW sequence. CONCLUSION: MR imaging can be helpful in revealing DAI lesions in patients with normal CT scan findings after MTBI. FLAIR, GRE and DW sequences are superior to conventional spin-echo images in detecting DAI lesions.
PURPOSE: To evaluate the occurrence and distribution of mild traumatic brain injury (MTBI) caused by diffuse axonal injury (DAI) using magnetic resonance (MR) imaging and to attempt to correlate MR findings with post-concussion symptoms (PCS). PATIENTS AND METHODS: Forty MTBI patients (mean age: 32.5 years) with normal cranial computed tomography (CT) findings were examined with standard MR protocol including T(1)-weighted, T(2)-weighted, fluid attenuated inversion recovery (FLAIR), gradient echo (GRE) and diffusion-weighted (DW) sequences. MR imaging was performed within 24 hours of injury. The lesions were classified as DAI based on their location and morphologic appearance. RESULTS: In MR imaging of five (12.5%) of the patients, the lesions compatible with DAI were observed. Four patients (10%) had the foci of low signal intensity compatible with hemorrhagic shear injury on the GRE sequence, and five (12.5%) patients had high signal intensity on FLAIR and DW sequence. CONCLUSION: MR imaging can be helpful in revealing DAI lesions in patients with normal CT scan findings after MTBI. FLAIR, GRE and DW sequences are superior to conventional spin-echo images in detecting DAI lesions.
Authors: Kai Zhang; Brian Johnson; Michael Gay; Silvina G Horovitz; Mark Hallett; Wayne Sebastianelli; Semyon Slobounov Journal: J Neurotrauma Date: 2012-03-20 Impact factor: 5.269
Authors: Jonathan O Swanson; Monica S Vavilala; Jin Wang; Sumit Pruthi; James Fink; Kenneth M Jaffe; Dennis Durbin; Thomas Koepsell; Nancy Temkin; Frederick P Rivara Journal: Pediatr Radiol Date: 2012-03-21
Authors: Trevor C Wu; Elisabeth A Wilde; Erin D Bigler; Ragini Yallampalli; Stephen R McCauley; Maya Troyanskaya; Zili Chu; Xiaoqi Li; Gerri Hanten; Jill V Hunter; Harvey S Levin Journal: J Neurotrauma Date: 2010-02 Impact factor: 5.269
Authors: Harald Schrader; Dalia Mickeviciene; Rymante Gleizniene; Silvija Jakstiene; Danguole Surkiene; Lars Jacob Stovner; Diana Obelieniene Journal: BMC Med Imaging Date: 2009-06-17 Impact factor: 1.930