Literature DB >> 18691443

Good glycaemic control: an international perspective on bridging the gap between theory and practice in type 2 diabetes.

E S Kilpatrick1, A K Das, C Orskov, K Berntorp.   

Abstract

BACKGROUND: Good glycaemic control is crucial in reducing the risk of diabetes-related complications. Despite the availability of evidence-based treatment guidelines, glycaemic control appears to remain suboptimal in most countries.
OBJECTIVES: In this commentary we outline the extent to which diabetes guideline targets on HbA(1c) are being met in clinical practice and--where targets are being missed--to identify potential reasons for this shortfall. Furthermore, we discuss possible actions that may improve glycaemic control.
METHODS: A literature search of MEDLINE using 20 core terms was conducted to help assess the state of glycaemic control in patients with type 2 diabetes worldwide.
RESULTS: Despite clinical guidelines, evidence suggests that glycaemic control is suboptimal in most parts of the world, with average HbA(1c) values varying from 7.0% to 12.6% and thus above virtually all HbA(1c) recommendations. The potential reasons for this shortfall are numerous. However, lack of diabetes education and awareness of HbA(1c) appear to be particularly important. A number of education initiatives from around the world have been shown to improve HbA(1c) levels significantly and thus improve standards of care.
CONCLUSIONS: Poor glycaemic control in patients with type 2 diabetes appears to be a worldwide problem. As the global rise in diabetes (and its complications) seems destined to affect many less affluent countries, it is essential that appropriate steps are taken to address the barriers to good glycaemic control and ultimately improve outcomes for all people with type 2 diabetes.

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Year:  2008        PMID: 18691443     DOI: 10.1185/03007990802347209

Source DB:  PubMed          Journal:  Curr Med Res Opin        ISSN: 0300-7995            Impact factor:   2.580


  8 in total

1.  Delay in starting insulin after failure of other treatments in patients with type 2 diabetes mellitus.

Authors:  I Zografou; Mwj Strachan; J McKnight
Journal:  Hippokratia       Date:  2014 Oct-Dec       Impact factor: 0.471

Review 2.  Novel insights into the relationship between diabetes and osteoporosis.

Authors:  Francisco J A de Paula; Mark C Horowitz; Clifford J Rosen
Journal:  Diabetes Metab Res Rev       Date:  2010-10-11       Impact factor: 4.876

3.  A new-generation ultra-long-acting basal insulin with a bolus boost compared with insulin glargine in insulin-naive people with type 2 diabetes: a randomized, controlled trial.

Authors:  Tim Heise; Cees J Tack; Robert Cuddihy; Jaime Davidson; Didier Gouet; Andreas Liebl; Enrique Romero; Henriette Mersebach; Patrik Dykiel; Rolf Jorde
Journal:  Diabetes Care       Date:  2011-02-01       Impact factor: 19.112

Review 4.  Insulin initiation in patients with type 2 diabetes mellitus: treatment guidelines, clinical evidence and patterns of use of basal vs premixed insulin analogues.

Authors:  Allan Vaag; Søren S Lund; Sørens Lund
Journal:  Eur J Endocrinol       Date:  2011-09-19       Impact factor: 6.664

5.  Insulin degludec compared with insulin glargine in insulin-naïve patients with type 2 diabetes: A 26-week, randomized, controlled, Pan-Asian, treat-to-target trial.

Authors:  Yukiko Onishi; Yasuhiko Iwamoto; Soon Jib Yoo; Per Clauson; Søren C Tamer; Sungwoo Park
Journal:  J Diabetes Investig       Date:  2013-06-03       Impact factor: 4.232

6.  Patient perceptions of their glycemic control and its influence on type 2 diabetes outcomes: an international survey of online communities.

Authors:  Kristina Simacek; Christopher Curran; Peter Fenici; Ricardo Garcia-Sanchez
Journal:  Patient Prefer Adherence       Date:  2019-02-18       Impact factor: 2.711

7.  Descriptions of health states associated with increasing severity and frequency of hypoglycemia: a patient-level perspective.

Authors:  Stewart B Harris; Kamlesh Khunti; Mona Landin-Olsson; Claus B Galbo-Jørgensen; Mette Bøgelund; Barrie Chubb; Jens Gundgaard; Marc Evans
Journal:  Patient Prefer Adherence       Date:  2013-09-16       Impact factor: 2.711

8.  Differences in glycemic control across world regions: a post-hoc analysis in patients with type 2 diabetes mellitus on dual antidiabetes drug therapy.

Authors:  H Brath; P M Paldánius; G Bader; W M Kolaczynski; P M Nilsson
Journal:  Nutr Diabetes       Date:  2016-07-04       Impact factor: 5.097

  8 in total

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