Literature DB >> 18691145

Wound healing agents: the role of natural and non-natural products in drug development.

Angelo de Fátima1, Luzia V Modolo, Andréia C Conegero Sanches, Raphael R Porto.   

Abstract

Impaired wound healing leads to infection and tissue necrosis. This has spurred the search for wound healing agents derived from natural and non-natural sources. Although natural products are widely used as lead compounds for the design of therapeutic drugs, few studies have looked for potential wound healing compounds in nature. In this review, we briefly discuss each phase of the wound healing process. Examples of natural and non-natural products with wound healing activities are listed, and the structure-activity relationship of fifty one compounds are described. An understanding of how these compounds exert their activities in biological systems is essential for their future development and application as wound healing agents.

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Year:  2008        PMID： 18691145     DOI： 10.2174/138955708785132738

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  15 in total

1.  Wound healing evaluation of self-nanoemulsifying drug delivery system containing Piper cubeba essential oil.

Authors:  Faiyaz Shakeel; Prawez Alam; Md Khalid Anwer; Saleh A Alanazi; Ibrahim A Alsarra; Mohammed H Alqarni
Journal:  3 Biotech       Date:  2019-02-14       Impact factor: 2.406

Review 2.  Nitric oxide release: part II. Therapeutic applications.

Authors:  Alexis W Carpenter; Mark H Schoenfisch
Journal:  Chem Soc Rev       Date:  2012-02-24       Impact factor: 54.564

3.  Nitric oxide-releasing polyurethane/S-nitrosated keratin mats for accelerating wound healing.

Authors:  Jie Dou; Rong Yang; Xingxing Jin; Pengfei Li; Xiao Han; Lijuan Wang; Bo Chi; Jian Shen; Jiang Yuan
Journal:  Regen Biomater       Date:  2022-02-02

Review 4.  Silver nanoparticles as real topical bullets for wound healing.

Authors:  Thirumurugan Gunasekaran; Tadele Nigusse; Magharla Dasaratha Dhanaraju
Journal:  J Am Coll Clin Wound Spec       Date:  2012-06-04

5.  A homeopathic remedy from arnica, marigold, St. John's wort and comfrey accelerates in vitro wound scratch closure of NIH 3T3 fibroblasts.

Authors:  Katarina Hostanska; Matthias Rostock; Joerg Melzer; Stephan Baumgartner; Reinhard Saller
Journal:  BMC Complement Altern Med       Date:  2012-07-18       Impact factor: 3.659

6.  Anti-inflammatory and protective investigations on the effects of Theranekron® "an alcoholic extract of the Tarantula cubensis" on wound healing of peritoneal in the rat: an in vivo comparative study.

Authors:  Farajollah Adib-Hashemi; Farshad Farahmand; Shamim Fattah Hesari; Bijan Rezakhaniha; Ehsan Fallah; Amir Farshid Fayyaz; Masoomeh Dadpay
Journal:  Diagn Pathol       Date:  2015-04-02       Impact factor: 2.644

Review 7.  An overview on the potential of natural products as ureases inhibitors: A review.

Authors:  Luzia V Modolo; Aline X de Souza; Lívia P Horta; Débora P Araujo; Ângelo de Fátima
Journal:  J Adv Res       Date:  2014-10-13       Impact factor: 10.479

8.  In vivo wound healing and antiulcer properties of white sweet potato (Ipomoea batatas).

Authors:  Daniele Hermes; Débora N Dudek; Mariana D Maria; Lívia P Horta; Eliete N Lima; Ângelo de Fátima; Andréia C C Sanches; Luzia V Modolo
Journal:  J Adv Res       Date:  2012-07-06       Impact factor: 10.479

9.  Evaluation of cutaneous wound healing activity of Malva sylvestris aqueous extract in BALB/c mice.

Authors:  Mohammad Afshar; Behdad Ravarian; Mahmoud Zardast; Seyed Adel Moallem; Mohammad Hasanpour Fard; Masoomeh Valavi
Journal:  Iran J Basic Med Sci       Date:  2015-06       Impact factor: 2.699

10.  A novel self-nanoemulsifying drug delivery system for curcumin used in the treatment of wound healing and inflammation.

Authors:  Niyaz Ahmad; Rizwan Ahmad; Ali Al-Qudaihi; Salman Edrees Alaseel; Ibrahim Zuhair Fita; Mohammed Saifuddin Khalid; Faheem Hyder Pottoo; Srinivasa Rao Bolla
Journal:  3 Biotech       Date:  2019-09-09       Impact factor: 2.893
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