Literature DB >> 18688904

Exploiting cross-amyloid interactions to inhibit protein aggregation but not function: nanomolar affinity inhibition of insulin aggregation by an IAPP mimic.

Aleksandra Velkova1, Marianna Tatarek-Nossol, Erika Andreetto, Aphrodite Kapurniotu.   

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Year:  2008        PMID： 18688904     DOI： 10.1002/anie.200801499

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  9 in total

1.  The sulfated triphenyl methane derivative acid fuchsin is a potent inhibitor of amyloid formation by human islet amyloid polypeptide and protects against the toxic effects of amyloid formation.

Authors:  Fanling Meng; Andisheh Abedini; Annette Plesner; Chris T Middleton; Kathryn J Potter; Martin T Zanni; C Bruce Verchere; Daniel P Raleigh
Journal:  J Mol Biol       Date:  2010-05-07       Impact factor: 5.469

2.  Insights into the consequences of co-polymerisation in the early stages of IAPP and Aβ peptide assembly from mass spectrometry.

Authors:  Lydia M Young; Rachel A Mahood; Janet C Saunders; Ling-Hsien Tu; Daniel P Raleigh; Sheena E Radford; Alison E Ashcroft
Journal:  Analyst       Date:  2015-10-21       Impact factor: 4.616

3.  Interaction between amyloid beta peptide and an aggregation blocker peptide mimicking islet amyloid polypeptide.

Authors:  Nasrollah Rezaei-Ghaleh; Erika Andreetto; Li-Mei Yan; Aphrodite Kapurniotu; Markus Zweckstetter
Journal:  PLoS One       Date:  2011-05-25       Impact factor: 3.240

4.  Mechanistic perspective and functional activity of insulin in amylin aggregation.

Authors:  Michal Baram; Sharon Gilead; Ehud Gazit; Yifat Miller
Journal:  Chem Sci       Date:  2018-04-16       Impact factor: 9.825

5.  The Human Host-Defense Peptide Cathelicidin LL-37 is a Nanomolar Inhibitor of Amyloid Self-Assembly of Islet Amyloid Polypeptide (IAPP).

Authors:  Valentina Armiento; Kathleen Hille; Denise Naltsas; Jennifer S Lin; Annelise E Barron; Aphrodite Kapurniotu
Journal:  Angew Chem Int Ed Engl       Date:  2020-04-30       Impact factor: 15.336

6.  Characterization of insulin cross-seeding: the underlying mechanism reveals seeding and denaturant-induced insulin fibrillation proceeds through structurally similar intermediates.

Authors:  Mohsen Akbarian; Maryam Kianpour; Reza Yousefi; Ali Akbar Moosavi-Movahedi
Journal:  RSC Adv       Date:  2020-08-13       Impact factor: 4.036

Review 7.  Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology.

Authors:  Rehana Akter; Ping Cao; Harris Noor; Zachary Ridgway; Ling-Hsien Tu; Hui Wang; Amy G Wong; Xiaoxue Zhang; Andisheh Abedini; Ann Marie Schmidt; Daniel P Raleigh
Journal:  J Diabetes Res       Date:  2015-11-15       Impact factor: 4.011

Review 8.  Peptide-Based Molecular Strategies To Interfere with Protein Misfolding, Aggregation, and Cell Degeneration.

Authors:  Valentina Armiento; Anna Spanopoulou; Aphrodite Kapurniotu
Journal:  Angew Chem Int Ed Engl       Date:  2019-11-28       Impact factor: 15.336

9.  Understanding co-polymerization in amyloid formation by direct observation of mixed oligomers.

Authors:  Lydia M Young; Ling-Hsien Tu; Daniel P Raleigh; Alison E Ashcroft; Sheena E Radford
Journal:  Chem Sci       Date:  2017-05-09       Impact factor: 9.825
  9 in total

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