Literature DB >> 18688665

Antibody response of HIV-infected patients to latent, cerebral and recently acquired toxoplasmosis.

L Machala1, M Malý, S Hrdá, H Rozsypal, M Stanková, P Kodym.   

Abstract

The aim of this longitudinal study with 626 HIV-infected patients was to evaluate the capability of serological tests in diagnosing the presence of Toxoplasma gondii infection in HIV-infected patients, as well as the potential impact of various treatment regimes on serological results. Low IgG antibody levels and stable or declining titres predominated. IgM positivity occurred in ten patients (one seroconversion, seven latent, two cerebral toxoplasmosis). Complement fixation test (CFT) titres >or=1:32 imply that the relative risk of cerebral toxoplasmosis is 6.84 (95% confidence interval [CI] 1.44-32.5) but with a predictive value of only 14.0% (95% CI 5.3-27.9). Values of specific antibodies are not biassed by antiretroviral treatment and/or prophylaxis for toxoplasmosis, and the detection of specific antibodies is very useful in the identification of T. gondii infection in the HIV-infected population, but the role of serology in predicting the clinical manifestation of T. gondii infection is limited.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 18688665     DOI： 10.1007/s10096-008-0600-9

Source DB:  PubMed          Journal:  Eur J Clin Microbiol Infect Dis        ISSN： 0934-9723            Impact factor:   3.267


  11 in total

1.  Prevalence and incidence of Toxoplasma infection in HIV-positive patients in the Czech Republic.

Authors:  Petr Kodym; Stepánka Hrdá; Ladislav Machala; Hanus Rozsypal; Marie Stanková; Marek Malý
Journal:  J Eukaryot Microbiol       Date:  2006       Impact factor: 3.346

2.  Evaluation of a commercial IgE ELISA in comparison with IgA and IgM ELISAs, IgG avidity assay and complement fixation for the diagnosis of acute toxoplasmosis.

Authors:  P Kodym; L Machala; H Rohácová; B Sirocká; M Malý
Journal:  Clin Microbiol Infect       Date:  2007-01       Impact factor: 8.067

3.  Incidence and risk factors of toxoplasmosis in a cohort of human immunodeficiency virus-infected patients: 1988-1995. HEMOCO and SEROCO Study Groups.

Authors:  F Belanger; F Derouin; L Grangeot-Keros; L Meyer
Journal:  Clin Infect Dis       Date:  1999-03       Impact factor: 9.079

4.  Long-term course and outcome in AIDS patients with cerebral toxoplasmosis.

Authors:  G Arendt; H J von Giesen; H Hefter; E Neuen-Jacob; H Roick; H Jablonowski
Journal:  Acta Neurol Scand       Date:  1999-09       Impact factor: 3.209

5.  The probability of acquiring primary Toxoplasma infection in HIV-infected patients: results of an 8-year retrospective study.

Authors:  I Reiter-Owona; R Bialek; J K Rockstroh; H M Seitz
Journal:  Infection       Date:  1998 Jan-Feb       Impact factor: 3.553

6.  Predictive value of Toxoplasma gondii antibody titres on the occurrence of toxoplasmic encephalitis in HIV-infected patients. ANRS 005/ACTG 154 Trial Group.

Authors:  F Derouin; C Leport; S Pueyo; P Morlat; B Letrillart; G Chêne; J L Ecobichon; B Luft; J Aubertin; R Hafner; J L Vildé; R Salamon
Journal:  AIDS       Date:  1996-11       Impact factor: 4.177

Review 7.  Toxoplasmic encephalitis in AIDS.

Authors:  B J Luft; J S Remington
Journal:  Clin Infect Dis       Date:  1992-08       Impact factor: 9.079

8.  Toxoplasma serology, parasitemia and antigenemia in patients at risk for toxoplasmic encephalitis.

Authors:  B R Dannemann; D M Israelski; G S Leoung; T McGraw; J Mills; J S Remington
Journal:  AIDS       Date:  1991-11       Impact factor: 4.177

9.  Prevalence of Toxoplasma infection in a cohort of homosexual men at risk of AIDS and toxoplasmic encephalitis.

Authors:  D M Israelski; J S Chmiel; L Poggensee; J P Phair; J S Remington
Journal:  J Acquir Immune Defic Syndr (1988)       Date:  1993-04

10.  Prevalence of latent toxoplasmosis and serological diagnosis of active infection in HIV-positive patients.

Authors:  J Zufferey; A Sugar; P Rudaz; J Bille; M P Glauser; J P Chave
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1993-08       Impact factor: 3.267
View more
  8 in total

1.  Serological survey and risk factors associated with Toxoplasma gondii infection among HIV-infected pregnant women attending Abuja Tertiary Hospital, Nigeria.

Authors:  Maryam Muhammad Zakari; Aliyu Yabagi Isah; Richard Offiong; Thairu Yunusa; Idris Nasir Abdullahi
Journal:  Malawi Med J       Date:  2020-09       Impact factor: 0.875

2.  Cryptococcal meningitis is a cause for cross-reactivity in cerebrospinal fluid assays for anti-Histoplasma, anti-Coccidioides and anti-Blastomyces antibodies.

Authors:  Nathan C Bahr; Anil A Panackal; Michelle M Durkin; Melinda L Smedema; Wesley Keown; Thomas E Davis; Luke Raymond-Guillen; Yoon-Dong Park; Kieren A Marr; Bettina C Fries; Peter R Williamson; David R Boulware; L Joseph Wheat
Journal:  Mycoses       Date:  2019-01-01       Impact factor: 4.377

3.  Latent Toxoplasma Infection and Higher Toxoplasma gondii Immunoglobulin G Levels Are Associated With Worse Neurocognitive Functioning in HIV-Infected Adults.

Authors:  Ajay R Bharti; Allen McCutchan; Reena Deutsch; Davey M Smith; Ronald J Ellis; Mariana Cherner; Steven P Woods; Robert K Heaton; Igor Grant; Scott L Letendre
Journal:  Clin Infect Dis       Date:  2016-10-28       Impact factor: 9.079

4.  Spectrum of AIDS Defining Opportunistic Infections in a Series of 77 Hospitalised HIV-infected Omani Patients.

Authors:  Abdullah A Balkhair; Zakariya K Al-Muharrmi; Shyam Ganguly; Ali A Al-Jabri
Journal:  Sultan Qaboos Univ Med J       Date:  2012-11-20

5.  Incidence, immunological and clinical characteristics of reactivation of latent Toxoplasma gondii infection in HIV-infected patients.

Authors:  P Kodym; M Malý; O Beran; D Jilich; H Rozsypal; L Machala; M Holub
Journal:  Epidemiol Infect       Date:  2014-05-22       Impact factor: 4.434

6.  Seroprevalence of Toxoplasma gondii among HIV Patients in Jahrom, Southern Iran.

Authors:  Hassan Rezanezhad; Fateme Sayadi; Enayatollah Shadmand; Seyed Dawood Mousavi Nasab; Hadi Rezaei Yazdi; Kavous Solhjoo; Akbar Kazemi; Monireh Maleki; Abbas Ahmadi Vasmehjani
Journal:  Korean J Parasitol       Date:  2017-02-28       Impact factor: 1.341

7.  The Effect of Latent Toxoplasma gondii Infection on the Immune Response in HIV-Infected Patients.

Authors:  Ondrej Beran; Petr Kodym; Marek Maly; Alzbeta Davidova; Gabriela Reinvartova; David Jilich; Michal Holub; Hanus Rozsypal
Journal:  Biomed Res Int       Date:  2015-07-12       Impact factor: 3.411

8.  Detection of Toxoplasma gondii in Acute and Chronic Phases of Infection in Immunocompromised Patients and Pregnant Women with Real-time PCR Assay Using TaqMan Fluorescent Probe.

Authors:  Parisa Mousavi; Hossein Mirhendi; Mehdi Mohebali; Saeedeh Shojaee; Hossein Keshavarz Valian; Shirzad Fallahi; Setareh Mamishi
Journal:  Iran J Parasitol       Date:  2018 Jul-Sep       Impact factor: 1.012
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.