Literature DB >> 18688147

Toxoplasma granuloma of brainstem: a rare case.

Anurag Gupta1, A Raja, A Mahadevan, S K Shankar.   

Abstract

Toxoplasmosis is a common opportunistic infection in patients with AIDS in whom it frequently presents as intracranial space-occupying lesions. In the immunocompetent patient the most common manifestation is as asymptomatic cervical lymphadenopathy which may be associated with vague systemic manifestations such as fever or myalgia. In very rare cases people with normal immunity may present with meningoencephalitis polymyositis or myocarditis. It is very rare to encounter a brainstem granuloma due to toxoplasma infection in such patients. We report a non-immunocompromised man who presented with multiple cranial nerve palsies due to a brainstem lesion, which turned out to be a toxoplasma granuloma. He recovered completely after a four-week course of Pyrimethamine and Sulphadoxine. An extensive search of the literature failed to reveal any prior reports of a similar nature. This case is being reported because of its rarity and the complete recovery made by the patient.

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Year:  2008        PMID: 18688147

Source DB:  PubMed          Journal:  Neurol India        ISSN: 0028-3886            Impact factor:   2.117


  3 in total

1.  Cerebral toxoplasmosis diagnosed by brain tissue PCR analysis in an immunocompetent patient.

Authors:  Giuseppe Pustorino; Edoardo Ferlazzo; Maria Stella Carpentieri; Vittoria Cianci; Sara Gasparini; Mauro Campello; Giovanni Luigi Milardi; Antonio Gangemi; Umberto Aguglia
Journal:  Neurol Clin Pract       Date:  2017-10

2.  Multiple intracerebral lesions in a young male.

Authors:  Madi Deepak; Achappa Basavaprabhu; Mahalingam Soundarya
Journal:  Afr Health Sci       Date:  2015-09       Impact factor: 0.927

3.  Intracranial inflammatory granuloma caused by toxoplasmosis.

Authors:  Zhi Hua Li; Fu You Guo; Zhong Quan Wang; Jing Cui
Journal:  Pathog Glob Health       Date:  2014-07       Impact factor: 2.894

  3 in total

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