| Literature DB >> 18684531 |
Basri Amasyali1, Sedat Kose, Hurkan Kursaklioglu, Cem Barcin, Ayhan Kilic.
Abstract
Monocyte chemoattractant protein-1 (MCP-1) plays a crucial role both in the initiation and progression of atherosclerosis. MCP-1 is a unique cytokine produced by macrophages, smooth muscle cells and endothelial cells within atherosclerotic plaques and seems to be a reliable indicator of atherosclerotic plaque burden. Higher levels of MCP-1 have been associated with a poor prognosis and increased risk for death independent of other risk factors in patients with acute coronary syndromes. In this paper, we discussed the role of MCP-1 in the pathogenesis of acute coronary syndromes.Entities:
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Year: 2008 PMID: 18684531 DOI: 10.1016/j.ijcard.2008.04.080
Source DB: PubMed Journal: Int J Cardiol ISSN: 0167-5273 Impact factor: 4.164