BACKGROUND AND METHODS: Scarce data are available on the prognostic role of uric acid (UA ) in patients with ST elevation myocardial infarction (STEMI). We aimed at assessing the relation between uric acid, measured on Intensive Cardiac Care Unit (ICCU) admission, and mortality at short term follow-up in 466 consecutive STEMI patients submitted to percutaneous coronary intervention (PCI), as well as its relation with inflammatory markers (C-reactive protein, CRP-fibrinogen, erythrocyte sedimentation rate ESR). RESULTS: Higher UA were detectable in the 21.5%.. In-hospital mortality was higher in patients with elevated UA (p<0.01 O.R. (95% C.I.): 3.9 (1.5-10.2)). At backward stepwise regression analysis UA resulted an independent predictor for in-hospital mortality (OR 1.82, 95%CI 1.15-2.86; p=0.01). CONCLUSION: Our data strongly suggest that in the acute phase of STEMI patients submitted to PCI, uric acid holds a prognostic role for in-hospital mortality. Copyright (c) 2008 Elsevier Ireland Ltd. All rights reserved.
BACKGROUND AND METHODS: Scarce data are available on the prognostic role of uric acid (UA ) in patients with ST elevation myocardial infarction (STEMI). We aimed at assessing the relation between uric acid, measured on Intensive Cardiac Care Unit (ICCU) admission, and mortality at short term follow-up in 466 consecutive STEMI patients submitted to percutaneous coronary intervention (PCI), as well as its relation with inflammatory markers (C-reactive protein, CRP-fibrinogen, erythrocyte sedimentation rate ESR). RESULTS: Higher UA were detectable in the 21.5%.. In-hospital mortality was higher in patients with elevated UA (p<0.01 O.R. (95% C.I.): 3.9 (1.5-10.2)). At backward stepwise regression analysis UA resulted an independent predictor for in-hospital mortality (OR 1.82, 95%CI 1.15-2.86; p=0.01). CONCLUSION: Our data strongly suggest that in the acute phase of STEMI patients submitted to PCI, uric acid holds a prognostic role for in-hospital mortality. Copyright (c) 2008 Elsevier Ireland Ltd. All rights reserved.
Authors: Alessandro Maloberti; C Giannattasio; M Bombelli; G Desideri; A F G Cicero; M L Muiesan; E A Rosei; M Salvetti; A Ungar; G Rivasi; R Pontremoli; F Viazzi; R Facchetti; C Ferri; B Bernardino; F Galletti; L D'Elia; P Palatini; E Casiglia; V Tikhonoff; C M Barbagallo; P Verdecchia; S Masi; F Mallamaci; M Cirillo; M Rattazzi; P Pauletto; P Cirillo; L Gesualdo; A Mazza; M Volpe; G Tocci; G Iaccarino; P Nazzaro; L Lippa; G Parati; R Dell'Oro; F Quarti-Trevano; G Grassi; A Virdis; C Borghi Journal: High Blood Press Cardiovasc Prev Date: 2020-03-10