AIMS: To assess to which extent lowering the level of HbA1c influences the 10-year risk of coronary heart disease (CHD) and all-cause mortality in patients with type 2 diabetes mellitus. METHODS: A literature search in Pubmed and Embase was performed, and the absolute risks in the results of the relevant and valid studies compared. RESULTS: Each study shows that with a decreasing percentage of HbA1c, both the risk of developing CHD and the risk of mortality decrease. CONCLUSIONS: Lowering HbA1c in type 2 diabetics decreases the absolute risk of developing CHD by 5-17%, as well as decreasing all-cause mortality by 6-15%.
AIMS: To assess to which extent lowering the level of HbA1c influences the 10-year risk of coronary heart disease (CHD) and all-cause mortality in patients with type 2 diabetes mellitus. METHODS: A literature search in Pubmed and Embase was performed, and the absolute risks in the results of the relevant and valid studies compared. RESULTS: Each study shows that with a decreasing percentage of HbA1c, both the risk of developing CHD and the risk of mortality decrease. CONCLUSIONS: Lowering HbA1c in type 2 diabetics decreases the absolute risk of developing CHD by 5-17%, as well as decreasing all-cause mortality by 6-15%.
Authors: Miyong T Kim; Kim B Kim; Boyun Huh; Tam Nguyen; Hae-Ra Han; Lee R Bone; David Levine Journal: Am J Prev Med Date: 2015-07-14 Impact factor: 5.043
Authors: Yubo Liu; Weibing Ye; Qian Chen; Yong Zhang; Chia-Hua Kuo; Mallikarjuna Korivi Journal: Int J Environ Res Public Health Date: 2019-01-07 Impact factor: 3.390
Authors: Yan Wei; Yingyao Chen; Yingnan Zhao; Russell Rothman; Jian Ming; Lei Wang; Xiaona Liu; Lizheng Shi; Wanghong Xu Journal: BMJ Open Diabetes Res Care Date: 2020-06
Authors: Javier Parra-Sánchez; María Moreno-Jiménez; Carla M Nicola; Ileana I Nocua-Rodríguez; María R Amegló-Parejo; Marlen Del Carmen-Peña; Carlos Cordero-Prieto; María J Gajardo-Barrena Journal: Aten Primaria Date: 2015-03-11 Impact factor: 1.137