Literature DB >> 18684108

Apoptotic sensitivity of murine IAP-deficient cells.

Julie M Rumble1, Mathieu J M Bertrand, Rebecca A Csomos, Casey W Wright, Lori Albert, Tak W Mak, Philip A Barker, Colin S Duckett.   

Abstract

Although numerous studies have implicated the IAPs (inhibitor of apoptosis proteins) in the control of apoptotic cell death, analyses of murine Iap-targeted cells have not revealed significant differences in their susceptibility to apoptosis. In the present study, we show that, under defined conditions, murine cells lacking XIAP (X-linked inhibitor of apoptosis) and c-IAP (cellular IAP) 2, but not c-IAP1, exhibit heightened apoptotic sensitivity to both intrinsic and extrinsic apoptotic stimuli.

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Year:  2008        PMID： 18684108      PMCID： PMC2676106          DOI： 10.1042/BJ20081188

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  26 in total

1.  A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors.

Authors:  C S Duckett; V E Nava; R W Gedrich; R J Clem; J L Van Dongen; M C Gilfillan; H Shiels; J M Hardwick; C B Thompson
Journal:  EMBO J       Date:  1996-06-03       Impact factor: 11.598

Review 2.  IAPs: what's in a name?

Authors:  Srinivasa M Srinivasula; Jonathan D Ashwell
Journal:  Mol Cell       Date:  2008-04-25       Impact factor: 17.970

3.  A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis.

Authors:  S M Srinivasula; R Hegde; A Saleh; P Datta; E Shiozaki; J Chai; R A Lee; P D Robbins; T Fernandes-Alnemri; Y Shi; E S Alnemri
Journal:  Nature       Date:  2001-03-01       Impact factor: 49.962

4.  Characterization of XIAP-deficient mice.

Authors:  H Harlin; S B Reffey; C S Duckett; T Lindsten; C B Thompson
Journal:  Mol Cell Biol       Date:  2001-05       Impact factor: 4.272

5.  Structural basis of IAP recognition by Smac/DIABLO.

Authors:  G Wu; J Chai; T L Suber; J W Wu; C Du; X Wang; Y Shi
Journal:  Nature       Date:  2000 Dec 21-28       Impact factor: 49.962

6.  Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition.

Authors:  C Du; M Fang; Y Li; L Li; X Wang
Journal:  Cell       Date:  2000-07-07       Impact factor: 41.582

7.  Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors.

Authors:  A G Uren; M Pakusch; C J Hawkins; K L Puls; D L Vaux
Journal:  Proc Natl Acad Sci U S A       Date:  1996-05-14       Impact factor: 11.205

8.  The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins.

Authors:  M Rothe; M G Pan; W J Henzel; T M Ayres; D V Goeddel
Journal:  Cell       Date:  1995-12-29       Impact factor: 41.582

9.  Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes.

Authors:  P Liston; N Roy; K Tamai; C Lefebvre; S Baird; G Cherton-Horvat; R Farahani; M McLean; J E Ikeda; A MacKenzie; R G Korneluk
Journal:  Nature       Date:  1996-01-25       Impact factor: 49.962

10.  Cellular inhibitor of apoptosis 1 and 2 are ubiquitin ligases for the apoptosis inducer Smac/DIABLO.

Authors:  Shimin Hu; Xiaolu Yang
Journal:  J Biol Chem       Date:  2003-01-13       Impact factor: 5.157
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  12 in total

1.  Nondegradative ubiquitination of apoptosis inducing factor (AIF) by X-linked inhibitor of apoptosis at a residue critical for AIF-mediated chromatin degradation.

Authors:  Eric M Lewis; Amanda S Wilkinson; Nicole Y Davis; David A Horita; John C Wilkinson
Journal:  Biochemistry       Date:  2011-12-02       Impact factor: 3.162

2.  Regulation of the copper chaperone CCS by XIAP-mediated ubiquitination.

Authors:  Graham F Brady; Stefanie Galbán; Xuwen Liu; Venkatesha Basrur; Jonathan D Gitlin; Kojo S J Elenitoba-Johnson; Thomas E Wilson; Colin S Duckett
Journal:  Mol Cell Biol       Date:  2010-02-12       Impact factor: 4.272

3.  Phenotypic differences between mice deficient in XIAP and SAP, two factors targeted in X-linked lymphoproliferative syndrome (XLP).

Authors:  Julie M Rumble; Karolyn A Oetjen; Paul L Stein; Pamela L Schwartzberg; Bethany B Moore; Colin S Duckett
Journal:  Cell Immunol       Date:  2009-06-13       Impact factor: 4.868

Review 4.  XIAP as a ubiquitin ligase in cellular signaling.

Authors:  S Galbán; C S Duckett
Journal:  Cell Death Differ       Date:  2010-01       Impact factor: 15.828

5.  Copper is a potent inhibitor of both the canonical and non-canonical NFκB pathways.

Authors:  Niall S Kenneth; George E Hucks; Andrew J Kocab; Annie L McCollom; Colin S Duckett
Journal:  Cell Cycle       Date:  2014-02-03       Impact factor: 4.534

6.  Distinctive effects of the cellular inhibitor of apoptosis protein c-IAP2 through stabilization by XIAP in glioblastoma multiforme cells.

Authors:  Wensheng Yang; Mariana Cooke; Colin S Duckett; Xiaolu Yang; Jay F Dorsey
Journal:  Cell Cycle       Date:  2014-01-22       Impact factor: 4.534

7.  Phosphorylation of eIF2α at serine 51 is an important determinant of cell survival and adaptation to glucose deficiency.

Authors:  Hala Muaddi; Mithu Majumder; Philippos Peidis; Andreas I Papadakis; Martin Holcik; Donalyn Scheuner; Randal J Kaufman; Maria Hatzoglou; Antonis E Koromilas
Journal:  Mol Biol Cell       Date:  2010-07-21       Impact factor: 4.138

8.  The E3 ubiquitin ligase cIAP1 binds and ubiquitinates caspase-3 and -7 via unique mechanisms at distinct steps in their processing.

Authors:  Young Eun Choi; Michael Butterworth; Srinivas Malladi; Colin S Duckett; Gerald M Cohen; Shawn B Bratton
Journal:  J Biol Chem       Date:  2009-03-03       Impact factor: 5.157

9.  Analysis of inhibitor of apoptosis protein family expression during mammary gland development.

Authors:  Thomas W Owens; Fiona M Foster; Jolanta Tanianis-Hughes; Julia Y Cheung; Lisa Brackenbury; Charles H Streuli
Journal:  BMC Dev Biol       Date:  2010-06-28       Impact factor: 1.978

10.  XIAP is not required for human tumor cell survival in the absence of an exogenous death signal.

Authors:  John Sensintaffar; Fiona L Scott; Robert Peach; Jeffrey H Hager
Journal:  BMC Cancer       Date:  2010-01-12       Impact factor: 4.430
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