Immunohistochemical detection of SNAP-25, NCAM, and insulin in the pancreas of nutria (Myocastor coypus).

Immunohistochemical study revealed three types of neuroendocrine contacts in nutria pancreas. In most cases, the pancreatic islets and individual endocrine cells were associated with a diffuse neural network. Integration of neural ganglia with the islets and innervation of endocrine cells by projections of ganglionic cells were detected. It is hypothesized that the structure of neuroendocrine interactions plays different roles in the regulation of endocrine secretion.