| Literature DB >> 18680966 |
E Innocent1, N K Gikonyo, M H H Nkunya.
Abstract
Long chain aliphatic methyl ketone series of C7-C15 were tested for repellency activity against the malaria transmitting mosquito Anopheles gambiae s.s. All methyl ketones produced a dose dependent (P < 0.001) repellency response with 2-tridecanone giving comparable protection efficacy to DEET at 10% and 1% concentrations. Aliphatic methyl ketones of C7-C10 had lower activity than those of C11-C15. However, within this range compounds with odd carbon atoms (2-undecanone, 2-tridecanone and 2-pentadecanone) were more effective than compounds with even carbon atoms (2-decanone and 2- dodecanone). Comparable repellency activity of 2-tridecanone to DEET show that, it may save as Anopheles gambiae s.s. mosquito repellent.Entities:
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Year: 2008 PMID： 18680966 DOI： 10.4314/thrb.v10i1.14342
Source DB: PubMed Journal: Tanzan J Health Res ISSN： 1821-9241